Does low-dose aspirin therapy complicate oral surgical procedures?

被引:90
作者
Ardekian, L [1 ]
Gaspar, R
Peled, M
Brener, B
Laufer, D
机构
[1] Rambam Med Ctr, Dept Oral & Maxillofacial Surg, IL-35254 Haifa, Israel
[2] Technion Israel Inst Technol, Bruce Rappaport Fac Med, IL-31096 Haifa, Israel
[3] Rambam Med Ctr, Thrombosis & Hemostasis Unit, IL-35254 Haifa, Israel
关键词
D O I
10.14219/jada.archive.2000.0176
中图分类号
R78 [口腔科学];
学科分类号
1003 [口腔医学];
摘要
Background. The fear of uncontrolled bleeding often prompts medical practitioners to stop aspirin intake for seven to 10 days before any surgical procedure. The authors initiated this study to evaluate the effect of aspirin on bleeding in patients undergoing oral surgery. Methods. The study group consisted of 39 patients who were scheduled to undergo dental extractions. AU patients were receiving 100 milligrams of aspirin daily on a regular basis. The authors randomly divided the patients into two groups: those who stopped the aspirin therapy before the procedure and those who continued the aspirin therapy. One hour before the procedures, all patients underwent a bleeding time test. In addition, the amount of bleeding during the procedure was measured. Results. The mean (+/- standard deviation) bleeding time was 1.8 +/- 0.47 minutes for patients who stopped aspirin therapy one week before the procedure. For patients who continued aspirin therapy, the bleeding time was 3.1 +/- 0.65 minutes. The difference was statistically significant (P = .004). However, both groups were within the normal bleeding time range, and in both groups, a local hemostatic method was:sufficient to control bleeding. No episodes of uncontrolled intraoperative or postoperative bleeding were noted. Conclusion. Low-dose aspirin therapy should not be stopped before oral surgery. Local hemostasis is sufficient to control bleeding. Clinical Implications. Patients receiving aspirin therapy to prevent blood dot formation may be subject to emboli formation if the treatment is stopped. The results of this study show that aspirin therapy should be continued throughout oral. surgical procedures. Local measures are sufficient to control any bleeding during surgery.
引用
收藏
页码:331 / 335
页数:5
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