A cognitive map for object memory in the hippocampus

被引：174

作者：

Manns, Joseph R. ^{[1
]}

Eichenbaum, Howard ^{[2
]}

机构：

[1] Emory Univ, Dept Psychol, Atlanta, GA 30322 USA

[2] Boston Univ, Ctr Memory & Brain, Boston, MA 02215 USA

来源：

LEARNING & MEMORY | 2009年 / 16卷 / 10期

关键词：

IMPAIRED RECOGNITION MEMORY; ENTORHINAL CORTEX; SPATIAL REPRESENTATION; EPISODIC MEMORY; PLACE CELLS; DECLARATIVE MEMORY; PERIRHINAL CORTEX; RATS; DAMAGE; NEURONS;

D O I：

10.1101/lm.1484509

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The hippocampus has been proposed to support a cognitive map, a mental representation of the spatial layout of an environment as well as the nonspatial items encountered in that environment. In the present study, we recorded simultaneously from 43 to 61 hippocampal pyramidal cells as rats performed an object recognition memory task in which novel and repeated objects were encountered in different locations on a circular track. Multivariate analyses of the neural data indicated that information about object identity was represented secondarily to the primary information dimension of object location. In addition, the neural data related to performance on the recognition memory task. The results suggested that objects were represented as points of interest on the hippocampal cognitive map and that this map was useful in remembering encounters with particular objects in specific locations.

引用

页码：616 / 624

页数：9

共 42 条

[1] Differential effects of damage within the hippocampal region on memory for a natural, nonspatial odor-odor association [J].