The PROSITE database

被引：671

作者：

Hulo, Nicolas

Bairoch, Amos

Bulliard, Virginie

Cerutti, Lorenzo

De Castro, Edouard

Langendijk-Genevaux, Petra S.

Pagni, Marco

Sigrist, Christian J. A.

机构：

[1] Ctr Med Univ Geneva, SIB, CH-1211 Geneva 4, Switzerland

[2] UNIL, BEP, SIB, CH-1066 Epalinges, Switzerland

来源：

NUCLEIC ACIDS RESEARCH | 2006年 / 34卷

关键词：

D O I：

10.1093/nar/gkj063

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The PROSITE database consists of a large collection of biologically meaningful signatures that are described as patterns or profiles. Each signature is linked to a documentation that provides useful biological information on the protein family, domain or functional site identified by the signature. The PROSITE database is now complemented by a series of rules that can give more precise information about specific residues. During the last 2 years, the documentation and the ScanProsite web pages were redesigned to add more functionalities. The latest version of PROSITE (release 19.11 of September 27, 2005) contains 1329 patterns and 552 profile entries. Over the past 2 years more than 200 domains have been added, and now 52% of UniProtKB/Swiss-Prot entries (release 48.1 of September 27, 2005) have a cross-reference to a PROSITE entry. The database is accessible at http://www.expasy.org/prosite/.

引用

页码：D227 / D230

页数：4

共 8 条

[1] Automated annotation of microbial proteomes in SWISS-PROT [J].

Gattiker, A ;

Michoud, K ;

Rivoire, C ;

Auchincloss, AH ;

Coudert, E ;

Lima, T ;

Kersey, P ;

Pagni, M ;

Sigrist, CJA ;

Lachaize, C ;

Veuthey, AL ;

Gasteiger, E ;

Bairoch, A .

COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2003, 27 (01) :49-58

[2] MSDsite: A database search and retrieval system for the analysis and viewing of bound ligands and active sites [J].

Golovin, A ;

Dimitropoulos, D ;

Oldfield, T ;

Rachedi, A ;

Henrick, K .

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2005, 58 (01) :190-199

[3]

Hofmann K, 2000, Brief Bioinform, V1, P167, DOI 10.1093/bib/1.2.167

[4] Recent improvements to the PROSITE database [J].

Hulo, N ;

Sigrist, CJA ;

Le Saux, V ;

Langendijk-Genevaux, PS ;

Bordoli, L ;

Gattiker, A ;

De Castro, E ;

Bucher, P ;

Bairoch, A .

NUCLEIC ACIDS RESEARCH, 2004, 32 :D134-D137

[5] Mechanisms and functions of EPH and ephrin signalling [J].

Kullander, K ;

Klein, R .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2002, 3 (07) :475-486

[6] Expression of a kinase-defective Eph-like receptor in the normal human brain [J].

Matsuoka, H ;

Iwata, N ;

Ito, M ;

Shimoyama, M ;

Nagata, A ;

Chihara, K ;

Takai, S ;

Matsui, T .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 235 (03) :487-492

[7]

Sigrist Christian J A, 2002, Brief Bioinform, V3, P265, DOI 10.1093/bib/3.3.265

[8] ProRule: a new database containing functional and structural information on PROSITE profiles [J].

Sigrist, CJA ;

De Castro, E ;

Langendijk-Genevaux, PS ;

Le Saux, V ;

Bairoch, A ;

Hulo, N .

BIOINFORMATICS, 2005, 21 (21) :4060-4066

← 1 →