Fluorescent natural products as probes and tracers in biology

被引:86
作者
Duval, Romain [1 ]
Duplais, Christophe [2 ]
机构
[1] Univ Paris 05, MERIT Mere & Enfant Face Infect Trop, IRD, UMR 216, 4 Ave Observ, F-75006 Paris, France
[2] Univ Guyane, Univ Antilles, EcoFoG Ecol Forets Guyane, AgroParisTech,CNRS,INRA,Cirad,UMR 8172, 23 Ave Pasteur, F-97300 Cayenne, France
关键词
INTRAMOLECULAR PROTON-TRANSFER; ANTIBIOTIC AMPHOTERICIN-B; POLYENE FATTY-ACIDS; CHLOROPHYLL-A-PROTEIN; DISEASE TYPE-C; LIPID-PEROXIDATION; PARINARIC ACID; LIQUID-CHROMATOGRAPHY; BENZOPHENANTHRIDINE ALKALOIDS; CAPILLARY-ELECTROPHORESIS;
D O I
10.1039/c6np00111d
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Fluorescence is a remarkable property of many natural products in addition to their medicinal and biological values. Herein, we provide a review on these peculiar secondarymetabolites to stimulate prospecting of them as original fluorescent tracers, endowed with unique photophysical properties and with applications in most fields of biology. The compounds are spectrally categorized (i.e. fluorescing from violet to the near infra-red) and further structurally classified within each category. Natural products selected for their high impact in modern fluorescence-based biological studies are highlighted throughout the article. Finally, we discuss aspects of chemical ecology where fluorescent natural products might have key evolutionary roles and thus open new research directions in the field.
引用
收藏
页码:161 / 193
页数:33
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