Biological mechanism of shockwave in bone

被引：79

作者：

Cheng, Jai-Hong ^{[1
,2
,3
]}

Wang, Ching-Jen ^{[1
,2
,4
]}

机构：

[1] Kaohsiung Chang Gung Mem Hosp, Ctr Shockwave Med & Tissue Engn, Kaohsiung 833, Taiwan

[2] Chang Gung Univ, Coll Med, Kaohsiung, Taiwan

[3] Kaohsiung Chang Gung Mem Hosp, Med Res, Kaohsiung 833, Taiwan

[4] Kaohsiung Chang Gung Mem Hosp, Dept Orthoped Surg, Kaohsiung 833, Taiwan

来源：

INTERNATIONAL JOURNAL OF SURGERY | 2015年 / 24卷

关键词：

Biological mechanism; Shockwave; Bone; EXTRACORPOREAL SHOCKWAVE; WAVE THERAPY; SEGMENTAL DEFECT; IN-VIVO; IGF-I; RATS; OSTEOARTHRITIS; KNEE; RABBITS; ERK;

D O I：

10.1016/j.ijsu.2015.06.059

中图分类号：

R61 [外科手术学];

学科分类号：

100210 [外科学];

摘要：

Shockwave is a rapid, short duration acoustic wave that carries energy and can propagate through tissue medium. This kind of physical force can be a mechanical stimulus that induces biological effects in living tissue. Extracorporeal shockwave therapy (ESWT) acts as a mechanical stimulus which promotes biological healing processes through a mechanotransduction. The biological effects of ESWT are reported such as tissue regeneration, wound healing, angiogenesis, bone remodeling, and anti-inflammation. Until now, however, little is known about the basic mechanism of action of this type of therapy. This article describes the molecular mechanism on the current status of ESWT with pre-clinical and clinical applications for treating disorders in bone. (C) 2015 IJS Publishing Group Limited. Published by Elsevier Ltd. All rights reserved.

引用

页码：143 / 146

页数：4

共 38 条

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