Modular asymmetric synthesis of pochonin C.

被引：60

作者：

Barluenga, S ^{[1
]}

Lopez, P ^{[1
]}

Moulin, E ^{[1
]}

Winssinger, N ^{[1
]}

机构：

[1] Univ Strasbourg, Inst Sci & Ingn Supremol, F-67000 Strasbourg, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 26期

关键词：

asymmetric synthesis; conformation analysis; metathesis; natural products; total synthesis;

D O I：

10.1002/anie.200454108

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Back to its origins: Pochonin C was synthesized in 11 steps from the four fragments shown in the scheme. This asymmetric synthesis and the conversion of pochonin C into radicicol defines the configuration at the center bearing the chlorine atom as S. lpc = isopenocampheyl, PG = protecting group.

引用

页码：3467 / 3470

页数：4

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