Role of osteodensitometry in osteoporosis and osteopenia in psoriatic arthritis

被引:11
作者
Brihan, Ilarie [1 ]
Halmajan, Angelica [2 ]
Boda, Daniel [3 ]
Ianosi, Simona Laura [4 ]
Fekete, Gyula Laszlo [5 ]
Zdrinca, Mihaela [6 ]
机构
[1] Univ Oradea, Fac Med & Pharm, Dermatol Clin, Dermatol Dept, Oradea 410073, Romania
[2] Univ Oradea, Fac Social Humanist Sci, Psychol Dept, Oradea 410073, Romania
[3] Carol Davila Univ Med & Pharm, Natl Inst Diabet Nutr & Metab Dis NC Paulescu, Dermatol Res Lab, Bucharest 050474, Romania
[4] Univ Med & Pharm Craiova, Dermatol Dept, Craiova 200349, Romania
[5] George Emil Palade Univ Med Pharm Sci & Technol, Dermatol Clin, Dermatol Discipline, 12 Gheorghe Doja St, Targu Mures 540530, Romania
[6] Univ Oradea, Fac Med & Pharm, Preclin Disciplines Dept, 10 Piata 1 Decembrie, Oradea 410073, Romania
关键词
psoriatic arthritis; bone mineral density; osteoporosis; osteopenia; DEXA bone densitometry; BONE-MINERAL DENSITY; DISEASE;
D O I
10.3892/etm.2020.9318
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
100103 [病原生物学]; 100218 [急诊医学];
摘要
Dual-energy X-ray Absorptiometry (DEXA) determines the mineral contents for the spine, the proximal femur and the entire body. A group of 36 patients with psoriatic arthritis were chosen, with different types of arthropathy, from the total 82 patients with psoriatic arthritis in the study group, for which bone mineral density (BMD) was measured, using the DEXA technique. The chosen study group comprised 12 men, 12 premenopausal women and 12 menopausal women, with psoriatic joint damage and a group of 36 healthy individuals, divided based on the same criteria: Men, premenopausal and menopausal women. This study did not emphasize an association between the patient type and the presented bone demineralization type (chi (2)((2))=4.473, P=0.107) in men. In premenopausal women, there was a significant association between the patient type and the presented bone demineralization type (chi (2)((2))=8.778, P=0.012), as the female patients with psoriatic arthritis presented total and partial demineralization to a larger degree, compared with healthy individuals. In menopausal women, this study did not highlight an association between the patient type and the presented bone demineralization type (chi (2)((2))=4.523, P=0.104). Bone demineralization was significant in all three patient groups, both total and partial, in patients with psoriatic arthritis compared with healthy patients. Bone demineralization manifested as osteopenia, with T-scores ranging from -2.5 to -1, and not as osteoporosis. Determining B MD by DEXA technique revealed osteopenia to a higher degree within the group of patients with psoriatic arthritis compared with the healthy patients, as well as the absence of osteoporosis in psoriatic arthritis.
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页数:7
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