Hyperforin analogues from St. John's wort (Hypericum perforatum)

被引：105

作者：

Verotta, L

Appendino, G

Jakupovic, J

Bombardelli, E

机构：

[1] Dipartimento Chim Organ & Ind, I-20133 Milan, Italy

[2] Dipartimento Chim Sci & Tecnol Farmaco, I-10125 Turin, Italy

[3] Analyt AG, D-14473 Potsdam, Germany

[4] Indena SPA, I-20141 Milan, Italy

来源：

JOURNAL OF NATURAL PRODUCTS | 2000年 / 63卷 / 03期

关键词：

D O I：

10.1021/np9903752

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three oxygenated analogues of the prenylated phloroglucinol hyperforin (3-5) were isolated from the aerial parts of Hypericum perforatum and their structures elucidated by spectroscopic methods.

引用

页码：412 / 415

页数：4

共 13 条

[1]

Bombardelli Ezio, 1995, Fitoterapia, V66, P43

[2] THE RELATIVE STEREOCHEMISTRY OF HYPERFORIN - AN ANTIBIOTIC FROM HYPERICUM-PERFORATUM L [J].

BRONDZ, I ;

GREIBROKK, T ;

GROTH, PA ;

AASEN, AJ .

TETRAHEDRON LETTERS, 1982, 23 (12) :1299-1300

[3] THE ABSOLUTE-CONFIGURATION OF HYPERFORIN, AN ANTIBIOTIC FROM HYPERICUM-PERFORATUM-L, BASED ON THE CRYSTAL-STRUCTURE DETERMINATION OF ITS PARA-BROMOBENZOATE ESTER [J].

BRONDZ, I ;

GREIBROKK, T ;

GROTH, P ;

AASEN, AJ .

ACTA CHEMICA SCANDINAVICA SERIES A-PHYSICAL AND INORGANIC CHEMISTRY, 1983, 37 (03) :263-265

[4]

BYSTROV NS, 1975, TETRAHEDRON LETT, P2791

[5] Hyperforin as a possible antidepressant component of hypericum extracts [J].

Chatterjee, SS ;

Bhattacharya, SK ;

Wonnemann, M ;

Singer, A ;

Müller, WE .

LIFE SCIENCES, 1998, 63 (06) :499-510

[6] Antidepressant activity of Hypericum perforatum and hyperforin: The neglected possibility [J].

Chatterjee, SS ;

Noldner, M ;

Koch, E ;

Erdelmeier, C .

PHARMACOPSYCHIATRY, 1998, 31 :7-15

[7] Hyperforin, possibly the major non-nitrogenous secondary metabolite of Hypericum perforatum L. [J].

Erdelmeier, CAJ .

PHARMACOPSYCHIATRY, 1998, 31 :2-6

[8] SUBELLINONE, A POLYISOPRENYLATED PHLOROGLUCINOL DERIVATIVE FROM GARCINIA-SUBELLIPTICA [J].

FUKUYAMA, Y ;

KANESHI, A ;

TANI, N ;

KODAMA, M .

PHYTOCHEMISTRY, 1993, 33 (02) :483-485

[9] ADHYPERFORIN - A HOMOLOG OF HYPERFORIN FROM HYPERICUM-PERFORATUM [J].

MAISENBACHER, P ;

KOVAR, KA .

PLANTA MEDICA, 1992, 58 (03) :291-293

[10]

Orth HCJ, 1999, PHARMAZIE, V54, P76

← 1 2 →