cASCading specks

被引：13

作者：

Broderick, Lori ^{[1
,2
]}

Hoffman, Hal M. ^{[1
,2
,3
]}

机构：

[1] Univ Calif San Diego, Dept Pediat, San Diego, CA 92103 USA

[2] Rady Childrens Hosp San Diego, San Diego, CA USA

[3] Univ Calif San Diego, Dept Med, San Diego, CA 92103 USA

来源：

NATURE IMMUNOLOGY | 2014年 / 15卷 / 08期

关键词：

ASC; APOPTOSIS; PROTEIN;

D O I：

10.1038/ni.2942

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Inflammasome-driven inflammation extends into the extracellular space and to neighboring cells through the passive release of specks consisting of the adaptor ASC; this perpetuates the innate immune response and adds a dimension beyond interleukin 1 to autoinflammation.

引用

页码：698 / 700

页数：3

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