Hereditary thrombocytopenia and acute myeloid leukemia: a common link due to a germline mutation in the AML1 gene

被引:7
作者
Appelmann, Iris [1 ]
Linden, Tobias [2 ]
Rudat, Annika [1 ]
Mueller-Tidow, Carsten [1 ]
Berdel, Wolfgang E. [1 ]
Mesters, Rolf M. [1 ]
机构
[1] Univ Munster, Dept Med Hematol & Oncol, D-48129 Munster, Germany
[2] Univ Munster, Dept Pediat Pediat Hematol & Oncol, D-48129 Munster, Germany
关键词
AUTOSOMAL-DOMINANT MACROTHROMBOCYTOPENIA; DIFFERENTIATION; EXPRESSION;
D O I
10.1007/s00277-009-0722-x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1037 / 1038
页数:2
相关论文
共 16 条
[1]   The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia [J].
Castilla, LH ;
Garrett, L ;
Adya, N ;
Orlic, D ;
Dutra, A ;
Anderson, S ;
Owens, J ;
Eckhaus, M ;
Bodine, D ;
Liu, PP .
NATURE GENETICS, 1999, 23 (02) :144-146
[2]   Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia [J].
Higuchi, M ;
O'Brien, D ;
Kumaravelu, P ;
Lenny, N ;
Yeoh, EJ ;
Downing, JR .
CANCER CELL, 2002, 1 (01) :63-74
[3]   AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis [J].
Ichikawa, M ;
Asai, T ;
Saito, T ;
Yamamoto, G ;
Seo, S ;
Yamazaki, I ;
Yamagata, T ;
Mitani, K ;
Chiba, S ;
Hirai, H ;
Ogawa, S ;
Kurokawa, M .
NATURE MEDICINE, 2004, 10 (03) :299-304
[4]   Mutation of MYH9, encoding non-muscle myosin heavy chain A, in May-Hegglin anomaly [J].
Kelley, MJ ;
Jawien, W ;
Ortel, TL ;
Korczak, JF .
NATURE GENETICS, 2000, 26 (01) :106-108
[5]   Autosomal dominant macrothrombocytopenia with leukocyte inclusions (May-Hegglin anomaly) is linked to chromosome 22q12-13 [J].
Kelley, MJ ;
Jawien, W ;
Lin, A ;
Hoffmeister, K ;
Pugh, EW ;
Doheny, KF ;
Korczak, JF .
HUMAN GENETICS, 2000, 106 (05) :557-564
[6]   Hereditary cancer: Theme and variations [J].
Knudson, AG .
JOURNAL OF CLINICAL ONCOLOGY, 1997, 15 (10) :3280-3287
[7]   Mutations in the NMMHC-A gene cause autosomal dominant macrothrombocytopenia with leukocyte inclusions (May-Hegglin anomaly/Sebastian syndrome) [J].
Kunishima, S ;
Kojima, T ;
Matsushita, T ;
Tanaka, T ;
Tsurusawa, M ;
Furukawa, Y ;
Nakamura, Y ;
Okamura, T ;
Amemiya, N ;
Nakayama, T ;
Kamiya, T ;
Saito, H .
BLOOD, 2001, 97 (04) :1147-1149
[8]   Mutations of the AML1 gene in acute myeloid leukemia of FAB types M0 and M7 [J].
Langabeer, SE ;
Gale, RE ;
Rollinson, SJ ;
Morgan, GJ ;
Linch, DC .
GENES CHROMOSOMES & CANCER, 2002, 34 (01) :24-32
[9]   Dual mutations in the AML1 and FLT3 genes are associated with leukemogenesis in acute myeloblastic leukemia of the M0 subtype [J].
Matsuno, N ;
Osato, M ;
Yamashita, N ;
Yanagida, M ;
Nanri, T ;
Fukushima, T ;
Motoji, T ;
Kusumoto, S ;
Towatari, M ;
Suzuki, R ;
Naoe, T ;
Nishii, K ;
Shigesada, K ;
Ohno, R ;
Mitsuya, H ;
Ito, Y ;
Asou, N .
LEUKEMIA, 2003, 17 (12) :2492-2499
[10]   Thrombocytopenia, giant platelets, and leukocyte inclusion bodies (May-Hegglin anomaly): Clinical and laboratory findings [J].
Noris, P ;
Spedini, P ;
Belletti, S ;
Magrini, U ;
Balduini, CL .
AMERICAN JOURNAL OF MEDICINE, 1998, 104 (04) :355-360