Determination of water-soluble UV filters in sunscreen sprays by liquid chromatography

被引：32

作者：

Chisvert, A ^{[1
]}

Salvador, A ^{[1
]}

机构：

[1] Univ Valencia, Fac Quim, Dept Quim Analit, E-46100 Burjassot, Valencia, Spain

来源：

JOURNAL OF CHROMATOGRAPHY A | 2002年 / 977卷 / 02期

关键词：

sunscreens; cosmetics; benzophenones; terephthalylidene dicamphor sulfonic acid; phenylbenzimidazole sulphonic acid;

D O I：

10.1016/S0021-9673(02)01411-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Liquid chromatography was used for the determination of the three most used water-soluble UV filters, benzophenone-4 (BZ4), terephthalylidene dicamphor sulfonic acid (TDS), and phenylbenzimidazole sulphonic acid (PBS), in aqueous sunscreen sprays. A C-18 stationary phase and an isocratic mobile phase of EtOH-20 mM sodium acetate buffer of pH 4.6 (30:70, v/v) were used at a flow-rate of 0.5 ml min(-1). Mobile phase was also used as solvent for samples and standards. UV detection was at 313 nm. The analytical run took 5.5 min. The limits of detection were 0.5, 0.9 and 2 mug ml(-1) for BZ4, TDS and PBS, respectively. The proposed method does not involve highly toxic solvents. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：277 / 280

页数：4