Transdermal clonidine in the prophylaxis of episodic cluster headache: An open study

被引：20

作者：

Leone, M ^{[1
]}

Attanasio, A ^{[1
]}

Grazzi, L ^{[1
]}

Libro, G ^{[1
]}

DAmico, D ^{[1
]}

Moschiano, F ^{[1
]}

Bussone, G ^{[1
]}

机构：

[1] IST NEUROL CARLO BESTA, HEADACHE CTR, I-20133 MILAN, ITALY

来源：

HEADACHE | 1997年 / 37卷 / 09期

关键词：

episodic cluster headache; prophylaxis; transdermal clonidine;

D O I：

10.1046/j.1526-4610.1997.3709559.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Transdermal clonidine has recently been reported to be efficacious in the prophylaxis of cluster headache. A 2-week course of transdermal clonidine (5 mg the first week, 7.5 mg the second week) preceded by a 5-day run-in period, was administered to 16 patients with episodic cluster headache in an active cluster period. In 5 patients, the painful attacks disappeared after the seventh day of treatment. For the group as a whole, no significant variations in headache frequency, pain intensity, or attack duration ware observed between the run-in period and the first and second weeks of treatment (ANOVA). Further studies are necessary to clarify the effectiveness of transdermal clonidine in the prophylaxis of episodic cluster headache.

引用

页码：559 / 560

页数：2

共 3 条

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