Isolation and characterization of 1,3-dimethylisoguanine from the Bermudian sponge Amphimedon viridis

被引：33

作者：

Mitchell, SS

Whitehill, AB

TrapidoRosenthal, HG

Ireland, CM

机构：

[1] UNIV UTAH,DEPT MED CHEM,SALT LAKE CITY,UT 84112

[2] BERMUDA BIOL STN,FERRY REACH GE 01,BERMUDA

来源：

JOURNAL OF NATURAL PRODUCTS | 1997年 / 60卷 / 07期

关键词：

D O I：

10.1021/np970015j

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The new compound 1,3-dimethylisoguanine has been isolated and characterized from the Bermudian sponge Amphimedon viridis. Chemical conversion of the natural product to theophylline and 2D NMR methods were used to determine the position of the methyl groups on the purine ring. Analysis of the mass spectral fragmentation pattern allowed assignment of the purine ring as isoguanine.

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页码：727 / 728

页数：2

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