Primary Prophylaxis of Variceal Bleeding

被引：21

作者：

Simonetto, Douglas A. ^{[1
]}

Shah, Vijay H. ^{[1
]}

Kamath, Patrick S. ^{[1
]}

机构：

[1] Mayo Clin, Fiterman Ctr Digest Dis, Adv Liver Dis Study Grp,Gastroenterol Res Unit, Div Gastroenterol & Hepatol,Dept Physiol, Rochester, MN 55905 USA

来源：

CLINICS IN LIVER DISEASE | 2014年 / 18卷 / 02期

关键词：

Portal hypertension; Cirrhosis; Gastrointestinal hemorrhage; Endoscopy; beta-blockers; RANDOMIZED CONTROLLED-TRIAL; ENDOSCOPIC BAND LIGATION; PORTAL PRESSURE RESPONSE; BETA-BLOCKERS; ESOPHAGEAL-VARICES; CIRRHOTIC-PATIENTS; GASTROESOPHAGEAL VARICES; ISOSORBIDE-MONONITRATE; CONSENSUS WORKSHOP; PROPRANOLOL;

D O I：

10.1016/j.cld.2013.12.005

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Primary prevention of variceal bleeding is an important and long-debated topic in the management of patients with cirrhosis and esophageal varices. Prophylaxis is recommended for high-risk patients with small esophageal varices (advanced liver disease and/or presence of red wale marks) and those with medium/large varices. Nonselective p-blockers and endoscopic band ligation have been shown to be equally effective in primary prevention of variceal bleeding and are the only currently recommended therapies. Controversy still exists, however, regarding which one of these strategies is preferred. This article reviews the established recommendations and recent advances in the prevention of first esophageal variceal bleeding.

引用

页码：335 / +

页数：12

共 60 条

[1]

Nadolol plus spironolactone in the prophylaxis of first variceal bleed in nonascitic cirrhotic patients: A preliminary study [J].