Control of asthma in children: still unacceptable? A French cross-sectional study

被引:41
作者
de Blic, Jacques [1 ]
Boucot, Isabelle [2 ]
Pribil, Celine [2 ]
Robert, Jacques [3 ]
Huas, Dominique [4 ]
Marguet, Christophe [5 ]
机构
[1] Univ Paris 05, Hop Necker Enfants Malad, Serv Pneumol & Allergol Pediat, F-75015 Paris, France
[2] Lab GlaxoSmithKline, F-78163 Marly Le Roi, France
[3] Cabinet Pediat & Allergol, F-69120 Vaulx En Velin, France
[4] Fac Paris 7 Denis Diderot, Dept Med Gen, F-75870 Paris 18, France
[5] Hop Charles Nicolle, Serv Pediat, F-76031 Rouen, France
关键词
Asthma; Control; Children; Lung function; Treatment; ENVIRONMENTAL TOBACCO-SMOKE; 3RD NATIONAL-HEALTH; ALLERGIC RHINITIS; DISEASE MANAGEMENT; PASSIVE SMOKING; SEVERITY; EXACERBATIONS; OVERWEIGHT; DIFFICULT; EXPOSURE;
D O I
10.1016/j.rmed.2009.03.006
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Background: The goal of asthma management focuses on adequate control of asthma, although little is known about the optimal level of asthma control to be reached. The ELIOS study was conducted in France to address this lack of information. Methods: Cross-sectional study of asthmatic children (4-15 years) visiting their medical practitioner. The primary objective was to assess the level of asthma control with a 3-level composite score based on French (ANAES) guidelines criteria (optimal, acceptable, and unacceptable). Results: Asthma control, was assessed in 3431 children and classified as optimal (26%), acceptable (41.3%), and unacceptable (32.7%). When PEFR was studied, asthma control was optimal. in 23.0%, acceptable in 35.8% and unacceptable in 41.2% (p < 0.001) of children. Unacceptable asthma control was significantly associated with higher BMI (p = 0.002), more recent diagnosis of asthma (p = 0.008), passive exposure to parental tobacco smoke (p < 0.001), number of associated allergic diseases (p < 0.001), frequent respiratory tract infections (p < 0.001) and low socioeconomic status (p < 0.001). Multivariate analysis identified presence of respiratory tract infections (p < 0.0001), passive exposure to parental tobacco smoke (p = 0.009) and low socioeconomic status (p = 0.042) as variables associated with unacceptable asthma control. Conclusions: There is room for improvement in France as only 25% of asthmatic children are optimally controlled. Public health strategies should increase awareness among physicians and parents about the importance of using asthma control tools, eliminating exposure to tobacco smoke and treating associated allergic diseases. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1383 / 1391
页数:9
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