Mechanism and echo time dependence of the fast response in fMR

被引:5
作者
Dymond, RC
Norris, DG
机构
[1] Max Planck Inst. of Cogn. Neurosci., Leipzig
[2] Max Planck Inst. of Cogn. Neurosci., 04103 Leipzig
关键词
fast response; deoxyhemoglobin; functional spectroscopy; cortical activation;
D O I
10.1002/mrm.1910380102
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The fast response (FR) is an early reduction in the amplitude of the fMR signal occurring shortly after the onset of stimulation. Owing to its potential advantages in terms of temporal and spatial resolution, it may be of considerable significance in functional experiments, A model for the mechanism of the FR was developed which accounts for the fMRS finding that the amplitude of the dip decreases with increasing echo time, Two computer simulations that confirmed the predictions of the model and showed that it is possible to select optimal echo times for the detection of the FR were performed.
引用
收藏
页码:1 / 6
页数:6
相关论文
共 15 条
[1]   THE INTRAVASCULAR CONTRIBUTION TO FMRI SIGNAL CHANGE - MONTE-CARLO MODELING AND DIFFUSION-WEIGHTED STUDIES IN-VIVO [J].
BOXERMAN, JL ;
BANDETTINI, PA ;
KWONG, KK ;
BAKER, JR ;
DAVIS, TL ;
ROSEN, BR ;
WEISSKOFF, RM .
MAGNETIC RESONANCE IN MEDICINE, 1995, 34 (01) :4-10
[2]   OBSERVATION OF A FAST-RESPONSE IN FUNCTIONAL MR [J].
ERNST, T ;
HENNIG, J .
MAGNETIC RESONANCE IN MEDICINE, 1994, 32 (01) :146-149
[3]   MR CONTRAST DUE TO MICROSCOPICALLY HETEROGENEOUS MAGNETIC-SUSCEPTIBILITY - NUMERICAL SIMULATIONS AND APPLICATIONS TO CEREBRAL PHYSIOLOGY [J].
FISEL, CR ;
ACKERMAN, JL ;
BUXTON, RB ;
GARRIDO, L ;
BELLIVEAU, JW ;
ROSEN, BR ;
BRADY, TJ .
MAGNETIC RESONANCE IN MEDICINE, 1991, 17 (02) :336-347
[4]  
HENNIG J, 1995, P SMR 3 ANN M NIC FR, P449
[5]   DYNAMIC MAGNETIC-RESONANCE-IMAGING OF HUMAN BRAIN ACTIVITY DURING PRIMARY SENSORY STIMULATION [J].
KWONG, KK ;
BELLIVEAU, JW ;
CHESLER, DA ;
GOLDBERG, IE ;
WEISSKOFF, RM ;
PONCELET, BP ;
KENNEDY, DN ;
HOPPEL, BE ;
COHEN, MS ;
TURNER, R ;
CHENG, HM ;
BRADY, TJ ;
ROSEN, BR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (12) :5675-5679
[6]   Interactions between electrical activity and cortical microcirculation revealed by imaging spectroscopy: Implications for functional brain mapping [J].
Malonek, D ;
Grinvald, A .
SCIENCE, 1996, 272 (5261) :551-554
[7]  
MCINTOSH J, 1996, P SOC MAGN RES MED 4, P284
[8]   BOLD BASED FUNCTIONAL MRI AT 4-TESLA INCLUDES A CAPILLARY BED CONTRIBUTION - ECHO-PLANAR IMAGING CORRELATES WITH PREVIOUS OPTICAL IMAGING USING INTRINSIC SIGNALS [J].
MENON, RS ;
OGAWA, S ;
HU, XP ;
STRUPP, JP ;
ANDERSON, P ;
UGURBIL, K .
MAGNETIC RESONANCE IN MEDICINE, 1995, 33 (03) :453-459
[9]  
MENON RS, 1995, P SMR 3 ANN M NIC FR, P68
[10]   BRAIN MAGNETIC-RESONANCE-IMAGING WITH CONTRAST DEPENDENT ON BLOOD OXYGENATION [J].
OGAWA, S ;
LEE, TM ;
KAY, AR ;
TANK, DW .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (24) :9868-9872