MICROBIOLOGY Bacteria get vaccinated

被引:2
作者
Barrangou, Rodolphe [1 ]
Klaenhammer, Todd R. [1 ]
机构
[1] N Carolina State Univ, Dept Food Bioproc & Nutr Sci, Raleigh, NC 27695 USA
关键词
D O I
10.1038/513175a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
070301 [无机化学]; 070403 [天体物理学]; 070507 [自然资源与国土空间规划学]; 090105 [作物生产系统与生态工程];
摘要
Infection by defective bacterial viruses that cannot replicate has now been found to be the key feature enabling bacteria to rapidly develop adaptive immunity against functional viruses.
引用
收藏
页码:175 / 176
页数:2
相关论文
共 8 条
[1]
CRISPR provides acquired resistance against viruses in prokaryotes [J].
Barrangou, Rodolphe ;
Fremaux, Christophe ;
Deveau, Helene ;
Richards, Melissa ;
Boyaval, Patrick ;
Moineau, Sylvain ;
Romero, Dennis A. ;
Horvath, Philippe .
SCIENCE, 2007, 315 (5819) :1709-1712
[2]
Small CRISPR RNAs guide antiviral defense in prokaryotes [J].
Brouns, Stan J. J. ;
Jore, Matthijs M. ;
Lundgren, Magnus ;
Westra, Edze R. ;
Slijkhuis, Rik J. H. ;
Snijders, Ambrosius P. L. ;
Dickman, Mark J. ;
Makarova, Kira S. ;
Koonin, Eugene V. ;
van der Oost, John .
SCIENCE, 2008, 321 (5891) :960-964
[3]
The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA [J].
Garneau, Josiane E. ;
Dupuis, Marie-Eve ;
Villion, Manuela ;
Romero, Dennis A. ;
Barrangou, Rodolphe ;
Boyaval, Patrick ;
Fremaux, Christophe ;
Horvath, Philippe ;
Magadan, Alfonso H. ;
Moineau, Sylvain .
NATURE, 2010, 468 (7320) :67-71
[4]
Development and Applications of CRISPR-Cas9 for Genome Engineering [J].
Hsu, Patrick D. ;
Lander, Eric S. ;
Zhang, Feng .
CELL, 2014, 157 (06) :1262-1278
[5]
Adaptation in bacterial CRISPR-Cas immunity can be driven by defective phages [J].
Hynes, Alexander P. ;
Villion, Manuela ;
Moineau, Sylvain .
NATURE COMMUNICATIONS, 2014, 5
[6]
CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA [J].
Marraffini, Luciano A. ;
Sontheimer, Erik J. .
SCIENCE, 2008, 322 (5909) :1843-1845
[7]
CRISPR-Cas systems for editing, regulating and targeting genomes [J].
Sander, Jeffry D. ;
Joung, J. Keith .
NATURE BIOTECHNOLOGY, 2014, 32 (04) :347-355
[8]
Unravelling the structural and mechanistic basis of CRISPR-Cas systems [J].
van der Oost, John ;
Westra, Edze R. ;
Jackson, Ryan N. ;
Wiedenheft, Blake .
NATURE REVIEWS MICROBIOLOGY, 2014, 12 (07) :479-492