Asymmetric addition of achiral organomagnesium reagents or organolithiums to achiral aldehydes or ketones: a review

被引：104

作者：

Luderer, Matthew R. ^{[1
]}

Bailey, William F. ^{[2
]}

Luderer, Mark R. ^{[2
]}

Fair, Justin D. ^{[2
]}

Dancer, Robert J. ^{[3
]}

Sommer, Michael Bech ^{[3
]}

机构：

[1] Univ Pittsburgh, Dept Nat Sci, Greensburg, PA 15601 USA

[2] Univ Connecticut, Dept Chem, Storrs, CT 06269 USA

[3] H Lundbeck & Co AS, Proc Chem, DK-2500 Copenhagen, Denmark

来源：

TETRAHEDRON-ASYMMETRY | 2009年 / 20卷 / 09期

关键词：

3-AMINOPYRROLIDINE LITHIUM AMIDES; HIGHLY ENANTIOSELECTIVE ADDITION; N-BUTYLLITHIUM; GRIGNARD-REAGENTS; CHIRAL LIGANDS; CARBONYL-COMPOUNDS; ALKYLLITHIUM REAGENTS; ALKYLATION REACTIONS; TITANIUM COMPLEXES; TARTARIC ACID;

D O I：

10.1016/j.tetasy.2009.03.015

中图分类号：

O61 [无机化学];

学科分类号：

070301 [无机化学];

摘要：

The enantioselective preparation of chiral secondary and tertiary alcohols via addition of an achiral organomagnesium reagent or an organolithium to an achiral aldehyde or ketone in a chiral medium is reviewed. The review is written in chronological order and contains 113 references to literature through late 2008. (c) 2009 Elsevier Ltd. All rights reserved.

引用

页码：981 / 998

页数：18

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