Interactions between lipoteichoic acid and peptidoglycan from Staphylococcus aureus:: a structural and functional analysis

被引：35

作者：

Thiemermann, C ^{[1
]}

机构：

[1] St Bartholomews & Royal London Sch Med & Dent, William Harvey Res Inst, Dept Expt Med & Nephrol, London EC1M 6BQ, England

来源：

MICROBES AND INFECTION | 2002年 / 4卷 / 09期

关键词：

shock; lipoteichoic acid; peptidoglycan;

D O I：

10.1016/S1286-4579(02)01620-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The cell wall of Gram-positive bacteria contains lipoteichoic acid (LTA) and peptidoglycan (PepG), which synergise to cause shock and organ failure in animals, and to activate human blood to release proinflammatory cytokines. The structural elements within LTA and PepG that are essential for the observed synergism are discussed. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

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页码：927 / 935

页数：9

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