Asymmetric [4+3] cycloadditions from chiral alpha-chloro imines

被引：53

作者：

Kende, AS

Huang, H

机构：

[1] Department of Chemistry, University of Rochester, Rochester

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 19期

关键词：

D O I：

10.1016/S0040-4039(97)00649-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first asymmetric [4+3] cycloadditions of 2-aminoallyl cations derived from chiral a-chloro imines to furan and pyrrole systems are reported. The absolute configuration of the major enantiomer of the bicyclic ketone 4a derived from the cycloadducts has been elucidated, and possible rationales for the observed stereoselectivity are discussed. (C) 1997 Elsevier Science Ltd.

引用

页码：3353 / 3356

页数：4

共 15 条

[1]

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[2]

CIAVATTA ML, 1994, TETRAHEDRON LETT, V35, P7871, DOI 10.1016/S0040-4039(00)77394-1

[3] NUCLEAR MAGNETIC-RESONANCE ENANTIOMER REAGENTS - CONFIGURATIONAL CORRELATIONS VIA NUCLEAR MAGNETIC-RESONANCE CHEMICAL-SHIFTS OF DIASTEREOMERIC MANDELATE, O-METHYLMANDELATE, AND ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETATE (MTPA) ESTERS [J].