Organization, development and function of complex brain networks

被引:1492
作者
Sporns, O [1 ]
Chialvo, DR
Kaiser, M
Hilgetag, CC
机构
[1] Indiana Univ, Dept Psychol, Bloomington, IN 47405 USA
[2] Indiana Univ, Program Cognit, Bloomington, IN 47405 USA
[3] Indiana Univ, Program Neural Sci, Bloomington, IN 47405 USA
[4] Northwestern Univ, Sch Med, Dept Physiol, Chicago, IL 60611 USA
[5] IMEDEA, Inst Med Estudios Avanzados, E-07122 Palma de Mallorca, Spain
[6] Int Jacobs Univ Bremen, Sch Engn & Sci, D-28759 Bremen, Germany
关键词
D O I
10.1016/j.tics.2004.07.008
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Recent research has revealed general principles in the structural and functional organization of complex networks which are shared by various natural, social and technological systems. This review examines these principles as applied to the organization, development and function of complex brain networks. Specifically, we examine the structural properties of large-scale anatomical and functional brain networks and discuss how they might arise in the course of network growth and rewiring. Moreover, we examine the relationship between the structural substrate of neuroanatomy and more dynamic functional and effective connectivity patterns that underlie human cognition. We suggest that network analysis offers new fundamental insights into global and integrative aspects of brain function, including the origin of flexible and coherent cognitive states within the neural architecture.
引用
收藏
页码:418 / 425
页数:8
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