No association between particular DRD3 and DAT gene polymorphisms and manic-depressive illness in a Spanish sample

被引：31

作者：

GomezCasero, E

Perez de Castro, I

SaizRuiz, J

Llinares, C

FernandezPiqueras, J

机构：

[1] AUTONOMOUS UNIV MADRID, FAC CIENCIAS, DEPT BIOL, LAB GENET MOL HUMANA, E-28049 MADRID, SPAIN

[2] HOSP RAMON Y CAJAL, SERV PSIQUIATRIA, MADRID, SPAIN

[3] UNIV ALCALA DE HENARES, MADRID, SPAIN

来源：

PSYCHIATRIC GENETICS | 1996年 / 6卷 / 04期

关键词：

DAT; DNA gene polymorphisms; DRD3; manic-depression;

D O I：

10.1097/00041444-199624000-00007

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We have carried out an association study of a polymorphism in the 3'UTR of the dopamine transporter gene (DAT) and a polymorphism in the coding region of the D3 receptor gene (DRD3) in Spanish patients with manic depression and in controls. No significant differences in allelic and genotypic frequencies of either of these polymorphisms was found in patients compared with controls.

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页码：209 / 212

页数：4

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