Social and environmental malaria risk factors in urban areas of Ouagadougou, Burkina Faso

被引:82
作者
Baragatti, Meili [1 ]
Fournet, Florence [2 ]
Henry, Marie-Claire [3 ]
Assi, Serge [1 ,4 ]
Ouedraogo, Herman [5 ]
Rogier, Christophe [1 ]
Salem, Gerard [6 ]
机构
[1] IMTSSA, Parasite Biol & Epidemiol Res Dept, UMR 6236, F-13998 Marseille, France
[2] IRD, Environm Urbain & Transit Sanit Afr Ouest, Ouagadougou, Burkina Faso
[3] Ctr Muraz, Bobo Dioulasso, Burkina Faso
[4] Inst Natl Sante Publ, Inst Pierre Richet, Abidjan, Cote Ivoire
[5] IRSS CNRST, Ouagadougou, Burkina Faso
[6] Univ Paris 10, Lab Espace Sante & Terr, F-92001 Nanterre, France
来源
MALARIA JOURNAL | 2009年 / 8卷
关键词
SUB-SAHARAN AFRICA; ANOPHELES-GAMBIAE; RURAL-AREAS; CIRCUMSPOROZOITE ANTIBODY; COMBATING MALARIA; TROPICAL AFRICA; URBANIZATION; TRANSMISSION; EPIDEMIOLOGY; GHANA;
D O I
10.1186/1475-2875-8-13
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Background: Despite low endemicity, malaria remains a major health problem in urban areas where a high proportion of fevers are presumptively treated using anti-malarial drugs. Low acquired malaria immunity, behaviour of city-dwellers, access to health care and preventive interventions, and heterogenic suitability of urban ecosystems for malaria transmission contribute to the complexity of the malaria epidemiology in urban areas. Methods: The study was designed to identify the determinants of malaria transmission estimated by the prevalence of anti-circumsporozoite (CSP) antibodies, the prevalence and density of Plasmodium falciparum infection, and the prevalence of malarial disease in areas of Ouagadougou, Burkina-Faso. Thick blood smears, dried blood spots and clinical status have been collected from 3,354 randomly chosen children aged 6 months to 12 years using two cross-sectional surveys (during the dry and rainy seasons) in eight areas from four ecological strata defined according to building density and land tenure (regular versus irregular). Demographic characteristics, socio-economic information, and sanitary and environmental data concerning the children or their households were simultaneously collected. Dependent variables were analysed using mixed multivariable models with random effects, taking into account the clustering of participants within compounds and areas. Results: Overall prevalences of CSP-antibodies and P. falciparum infections were 7.7% and 16.6% during the dry season, and 12.4% and 26.1% during the rainy season, respectively, with significant differences according to ecological strata. Malaria risk was significantly higher among children who i) lived in households with lower economic or education levels, iii) near the hydrographic network, iv) in sparsely built-up areas, v) in irregularly built areas, vi) who did not use a bed net, vii) were sampled during the rainy season or ii) had traveled outside of Ouagadougou. Conclusion: Malaria control should be focused in areas which are irregularly or sparsely built-up or near the hydrographic network. Furthermore, urban children would benefit from preventive interventions (e. g. anti-vectorial devices or chemoprophylaxis) aimed at reducing malaria risk during and after travel in rural areas.
引用
收藏
页数:14
相关论文
共 46 条
[1]   Does irrigated urban agriculture influence the transmission of malaria in the city of Kumasi, Ghana? [J].
Afrane, YA ;
Klinkenberg, E ;
Drechsel, P ;
Owusu-Daaku, K ;
Garms, R ;
Kruppa, T .
ACTA TROPICA, 2004, 89 (02) :125-134
[2]   Malaria misdiagnosis: effects on the poor and vulnerable [J].
Amexo, M ;
Tolhurst, R ;
Barnish, G ;
Bates, I .
LANCET, 2004, 364 (9448) :1896-1898
[3]  
Assunçao RM, 1999, STAT MED, V18, P2147, DOI 10.1002/(SICI)1097-0258(19990830)18:16<2147::AID-SIM179>3.0.CO
[4]  
2-I
[5]  
Awolola T. S., 2007, Journal of Vector Borne Diseases, V44, P241
[6]  
Bogreau H, 2006, AM J TROP MED HYG, V74, P953
[7]  
CARNEVALE P, 1978, B WORLD HEALTH ORGAN, V56, P147
[8]  
Chinery W A, 1995, Afr J Med Med Sci, V24, P179
[9]  
CHINERY WA, 1984, J TROP MED HYG, V87, P75
[10]  
DABIRE E, 1990, MORBIDITE MORTALITE