Natural selection affects frequencies of AG and GT dinucleotides at the 5′ and 3′ ends of exons

被引：31

作者：

Eskesen, ST ^{[1
]}

Eskesen, FN ^{[1
]}

Ruvinsky, A ^{[1
]}

机构：

[1] Univ New England, Inst Genet & Bioinformat, Armidale, NSW 2351, Australia

来源：

GENETICS | 2004年 / 167卷 / 01期

关键词：

D O I：

10.1534/genetics.167.1.543

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

GT and AG, located at the 5' and 3' ends of introns, are important for correct splicing. It is anticipated that natural selection decreases frequency of AG and GT near the 5' and 3' ends of exons, preventing appearance of cryptic splicing sites. The data presented in this article support the expectation.

引用

页码：543 / 550

页数：8

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