Synthesis of the first photo-triggered pro-mitosene based on FR-900482

被引:29
作者
Williams, RM [1 ]
Rollins, SB [1 ]
Judd, TC [1 ]
机构
[1] Colorado State Univ, Dept Chem, Ft Collins, CO 80523 USA
基金
美国国家卫生研究院;
关键词
mitosene; photochemical trigger; aziridine; FR-900482; antitumor antibiotic;
D O I
10.1016/S0040-4020(99)01046-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A stereocontrolled synthesis of an eight-membered ring precursor to a photo-triggered mitosene is described. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:521 / 532
页数:12
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