Ultracompact biochemical sensor built with two-dimensional photonic crystal microcavity

被引:405
作者
Chow, E [1 ]
Grot, A [1 ]
Mirkarimi, LW [1 ]
Sigalas, M [1 ]
Girolami, G [1 ]
机构
[1] Agilent Technol, Palo Alto, CA 94304 USA
关键词
D O I
10.1364/OL.29.001093
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We report an experimental demonstration of an ultracompact biochemical sensor based on a two-dimensional photonic crystal microcavity. The microcavity, fabricated on a silicon-on-insulator substrate, is designed to have a resonant wavelength (lambda) near 1.5 mum. The transmission spectrum of the sensor is measured with different ambient refractive indices ranging from n = 1.0 to n = 1.5. From observation of the shift in resonant wavelength, a change in ambient refractive index of Deltan = 0.002 is readily apparent. The correspondence between absolute refractive index and resonant wavelength agrees with numerical calculation to within 4% accuracy. The evaporation of water in a 5% glycerol mixture is also used to demonstrate the capability for in situ time-resolved sensing. (C) 2004 Optical Society of America
引用
收藏
页码:1093 / 1095
页数:3
相关论文
共 15 条
[1]   Colorimetric resonant reflection as a direct biochemical assay technique [J].
Cunningham, B ;
Li, P ;
Lin, B ;
Pepper, J .
SENSORS AND ACTUATORS B-CHEMICAL, 2002, 81 (2-3) :316-328
[2]  
Joannopoulos J. D., 1995, PHOTONIC CRYSTALS
[3]   Block-iterative frequency-domain methods for Maxwell's equations in a planewave basis [J].
Johnson, SG ;
Joannopoulos, JD .
OPTICS EXPRESS, 2001, 8 (03) :173-190
[4]   Linear waveguides in photonic-crystal slabs [J].
Johnson, SG ;
Villeneuve, PR ;
Fan, SH ;
Joannopoulos, JD .
PHYSICAL REVIEW B, 2000, 62 (12) :8212-8222
[5]   PRINCIPLES OF BIOSENSING WITH AN EXTENDED COUPLING MATRIX AND SURFACE-PLASMON RESONANCE [J].
LIEDBERG, B ;
LUNDSTROM, I ;
STENBERG, E .
SENSORS AND ACTUATORS B-CHEMICAL, 1993, 11 (1-3) :63-72
[6]   Photonic band-gap microcavities in three dimensions [J].
Lin, SY ;
Fleming, JG ;
Sigalas, MM ;
Biswas, R ;
Ho, KM .
PHYSICAL REVIEW B, 1999, 59 (24) :R15579-R15582
[7]   A porous silicon-based optical interferometric biosensor [J].
Lin, VSY ;
Motesharei, K ;
Dancil, KPS ;
Sailor, MJ ;
Ghadiri, MR .
SCIENCE, 1997, 278 (5339) :840-843
[8]   Photonic crystal laser sources for chemical detection [J].
Loncar, M ;
Scherer, A ;
Qiu, YM .
APPLIED PHYSICS LETTERS, 2003, 82 (26) :4648-4650
[9]   Immobilization of antibodies in micropatterns for cell detection by optical diffraction [J].
Morhard, F ;
Pipper, J ;
Dahint, R ;
Grunze, M .
SENSORS AND ACTUATORS B-CHEMICAL, 2000, 70 (1-3) :232-242
[10]   Defect modes of a two-dimensional photonic crystal in an optically thin dielectric slab [J].
Painter, O ;
Vuckovic, J ;
Scherer, A .
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA B-OPTICAL PHYSICS, 1999, 16 (02) :275-285