The hereditary spastic paraplegias

被引：48

作者：

Reid, E ^{[1
]}

机构：

[1] Addenbrookes Hosp, Cambridge Inst Med Res, Dept Med Genet, Cambridge CB2 2XY, England

来源：

JOURNAL OF NEUROLOGY | 1999年 / 246卷 / 11期

基金：

英国惠康基金;

关键词：

hereditary spastic paraplegia; molecular genetics; review;

D O I：

10.1007/s004150050503

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The hereditary spastic paraplegias are a complex group of neurodegenerative conditions which are characterised by slowly progressive lower limb spasticity. This article describes the main clinical features of pure and complicated hereditary spastic paraplegias and summarises recent advances in our understanding of the molecular genetics of these conditions.

引用

页码：995 / 1003

页数：9

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