Distribution of oxygen across the surface of the human cornea during soft contact lens wear

被引:11
作者
Efron, N
Fitzgerald, JP
机构
[1] Eurolens Research, Dept. of Optom. and Vision Sciences, Univ. Manchester Inst. Sci. Technol., Manchester
[2] Dept. of Optom. and Vision Sciences, University of Melbourne, Parkville, Vic.
[3] Eurolens Research, Dept. of Optom. and Vision Sciences, Univ. Manchester Inst. Sci. Technol., Manchester M60 1QD
关键词
soft contact lens; tear mixing; cornea; blinking; equivalent oxygen percentage;
D O I
10.1097/00006324-199610000-00005
中图分类号
R77 [眼科学];
学科分类号
100212 [眼科学];
摘要
Purpose. To determine whether tear mixing occurs beneath soft contact tenses, we examined the effect of blinking on the oxygen distribution across the corneal surface beneath a nonuniform thickness lens. Methods. A custom-designed twin polarographic oxygen sensor assembly was used to simultaneously measure the equivalent oxygen percentage (EOP) at central and peripheral corneal locations of 10 human subjects beneath a -6.00 D thin-design hydroxyethyl mathacrylate (HEMA) lens. A -0.25 D lens served as a control. Each lens was worn for 5 min under static (no blinking) and dynamic (12 and 60 blinks/min) conditions. Results. A significantly greater EOP (p=0.006) was observed at the central (vs, peripheral) cornea during static and dynamic lens wear; central and peripheral oxygenation were unaffected by blinking. Conclusions. Tear mixing is insignificant beneath thin-design HEMA lenses; therefore, oxygenation across the corneal surface beneath such lenses is best predicted from the lens thickness profile rather than average thickness.
引用
收藏
页码:659 / 665
页数:7
相关论文
共 38 条
[1]
BENTLEY CR, 1983, AM J OPTOM PHYS OPT, V60, P960
[2]
BERGER RE, 1976, AM J OPTOM PHYSL OPT, V51, P441
[3]
BONANNO JA, 1986, AM J OPTOM PHYS OPT, V63, P520
[4]
BONANNO JA, 1985, AM J OPTOM PHYS OPT, V62, P74
[5]
Brennan N A, 1986, Clin Exp Optom, V69, P82, DOI 10.1111/j.1444-0938.1986.tb06794.x
[6]
Brennan N A, 1991, CLAO J, V17, P169
[7]
Brennan N A, 1986, Clin Exp Optom, V69, P120, DOI 10.1111/j.1444-0938.1986.tb06801.x
[8]
BRENNAN NA, 1987, ACTA OPHTHALMOL, V65, P556
[9]
A REVIEW OF THE THEORETICAL CONCEPTS, MEASUREMENT SYSTEMS AND APPLICATION OF CONTACT-LENS OXYGEN PERMEABILITY [J].
BRENNAN, NA ;
EFRON, N ;
HOLDEN, BA ;
FATT, I .
OPHTHALMIC AND PHYSIOLOGICAL OPTICS, 1987, 7 (04) :485-490
[10]
BRENNAN NA, 1987, CONTAX, V2, P12