Enabling multiscale modeling in systems medicine

被引：55

作者：

Wolkenhauer, Olaf ^{[1
,2
]}

Auffray, Charles ^{[3
]}

Brass, Olivier ^{[4
]}

Clairambault, Jean ^{[5
,6
,7
,8
]}

Deutsch, Andreas ^{[9
]}

Drasdo, Dirk ^{[7
,8
,10
]}

Gervasio, Francesco ^{[11
]}

Preziosi, Luigi ^{[12
]}

Maini, Philip ^{[13
]}

Marciniak-Czochra, Anna ^{[14
,15
]}

Kossow, Christina ^{[1
]}

Kuepfer, Lars ^{[16
,17
]}

Rateitschak, Katja ^{[1
]}

Ramis-Conde, Ignacio ^{[18
]}

Ribba, Benjamin ^{[19
]}

Schuppert, Andreas ^{[20
,21
]}

Smallwood, Rod ^{[22
]}

Stamatakos, Georgios ^{[23
]}

Winter, Felix ^{[1
,24
]}

Byrne, Helen ^{[25
,26
]}

机构：

[1] Univ Rostock, Dept Syst Biol & Bioinformat, D-18051 Rostock, Germany

[2] Univ Stellenbosch, Wallenberg Res Ctr, Stellenbosch Inst Adv Study, ZA-7600 Stellenbosch, South Africa

[3] Univ Lyon 1, Inst Biol Sci, CNRS, European Inst Syst Biol & Med, F-69100 Villeurbanne, France

[4] Sanofi Pasteur, F-69280 Marcy Letoile, France

[5] UPMC, INRIA Paris Rocquencourt, Lab Jacques Louis Lions, F-75005 Paris, France

[6] UPMC, Inst Univ Canc, F-75005 Paris, France

[7] INRIA Paris Rocquencourt, F-78153 Le Chesnay, France

[8] Univ Paris 06, CNRS UMR 7598, Lab Jacques Louis Lions, F-75005 Paris, France

[9] Tech Univ Dresden, Ctr Informat Serv & High Performance Comp, D-01062 Dresden, Germany

[10] Univ Leipzig, Interdisciplinary Ctr Bioinformat IZBI, D-04109 Leipzig, Germany

[11] UCL, Dept Chem, London WC1H 0AJ, England

[12] Politecn Torino, Dept Math Sci, I-10129 Turin, Italy

[13] Univ Oxford, Wolfson Ctr Math Biol, Oxford OX2 6GGUK, England

[14] Heidelberg Univ, Inst Appl Math, Interdisciplinary Ctr Sci Comp, D-69120 Heidelberg, Germany

[15] Heidelberg Univ, BIOQUANT, D-69120 Heidelberg, Germany

[16] Bayer Technol Serv GmbH, Computat Syst Biol, D-51368 Leverkusen, Germany

[17] Rhein Westfal TH Aachen, Inst Appl Microbiol, D-52056 Aachen, Germany

[18] Univ Castilla La Mancha, IMACI, E-13071 Ciudad Real, Spain

[19] Ecole Normale Super Lyon, NuMed, F-69342 Lyon, France

[20] Bayer Technol Serv GmbH, Technol Dev, D-51368 Leverkusen, Germany

[21] Rhein Westfal TH Aachen, Joint Res Ctr Computat Biomed, D-52056 Aachen, Germany

[22] Univ Sheffield, Kroto Res Inst, Sheffield S10 2TN, S Yorkshire, England

[23] Natl Tech Univ Athens, Inst Commun & Comp Syst, In Silico Oncol Grp, Zografos 15773, Greece

[24] ASD GmbH Rostock, D-18059 Rostock, Germany

[25] Univ Oxford, Sch Math Sci, Oxford OX1 3QD, England

[26] Univ Oxford, Dept Comp Sci, Oxford OX1 3QD, England

来源：

GENOME MEDICINE | 2014年 / 6卷

关键词：

Gene Regulatory Network; Multiscale Modeling; Recommended Action; Pharmacodynamic Model; System Medicine;

D O I：

10.1186/gm538

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

[No abstract available]

引用

页数：3