Chiral heterocycles by iminium ion cyclization

被引：401

作者：

Royer, J ^{[1
]}

Bonin, M ^{[1
]}

Micouin, L ^{[1
]}

机构：

[1] Univ Paris 05, CNRS, UMR 8638, Fac Sci Pharmaceut & Biol, F-75270 Paris 06, France

来源：

CHEMICAL REVIEWS | 2004年 / 104卷 / 05期

关键词：

D O I：

10.1021/cr020083x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This review aims to show the importance of the iminium ion cyclization in the enantioselective synthesis of various heterocycles. Focus is on iminium ions which formally can arise from the condensation of an aldehyde and a secondary amine. Cyclization reactions leading to the creation of a stereogenic center resulting in chiral nonracemic compounds are considered.

引用

页码：2311 / 2352

页数：42

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