Targeting Transcription Factors for Cancer Prevention-the Case of Nrf2

被引：15

作者：

Colburn, Nancy H. ^{[1
]}

Kensler, Thomas W. ^{[2
]}

机构：

[1] NCI, Lab Canc Prevent, Frederick, MD 21702 USA

[2] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Environm Hlth Sci, Baltimore, MD USA

来源：

CANCER PREVENTION RESEARCH | 2008年 / 1卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1158/1940-6207.CAPR-08-0025

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

[No abstract available]

引用

收藏

页码：153 / 155

页数：3

相关论文

共 18 条

[1]

Inflammation and cancer: How hot is the link? [J].

Aggarwal, Bharat B. ;

Shishodia, Shishir ;

Sandur, Santosh K. ;

Pandey, Manoj K. ;

Sethi, Gautam .

BIOCHEMICAL PHARMACOLOGY, 2006, 72 (11) :1605-1621

[2]

Nuclear factor-kappa B and cancer: its role in prevention and therapy [J].

Bharti, AC ;

Aggarwal, BB .

BIOCHEMICAL PHARMACOLOGY, 2002, 64 (5-6) :883-888

[3]

Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis [J].

Chan, KS ;

Sano, S ;

Kiguchi, K ;

Anders, J ;

Komazawa, N ;

Takeda, J ;

DiGiovanni, J .

JOURNAL OF CLINICAL INVESTIGATION, 2004, 114 (05) :720-728

[4]

Transcription factors as targets for cancer therapy [J].

Darnell, JE .

NATURE REVIEWS CANCER, 2002, 2 (10) :740-749

[5]

IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer [J].

Greten, FR ;

Eckmann, L ;

Greten, TF ;

Park, JM ;

Li, ZW ;

Egan, LJ ;

Kagnoff, MF ;

Karin, M .

CELL, 2004, 118 (03) :285-296

[6]

Divergent responses of chondrocytes and endothelial cells to shear stress: Cross-talk among COX-2, the phase 2 response, and apoptosis [J].

Healy, ZR ;

Lee, NH ;

Gao, XQ ;

Goldring, MB ;

Talalay, P ;

Kensler, TW ;

Konstantopoulos, K .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (39) :14010-14015

[7]

Progress in chemoprevention drug development: The promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer - A plan to move forward [J].

Kelloff, Gary J. ;

Lippman, Scott M. ;

Dannenberg, Andrew J. ;

Sigman, Caroline C. ;

Pearce, Homer L. ;

Reid, Brian J. ;

Szabo, Eva ;

Jordan, V. Craig ;

Spitz, Margaret R. ;

Mills, Gordon B. ;

Papadimitrakopoulou, Vali A. ;

Lotan, Reuben ;

Aggarwal, Bharat B. ;

Bresalier, Robert S. ;

Kim, Jeri ;

Arun, Banu ;

Lu, Karen H. ;

Thomas, Melanie E. ;

Rhodes, Helen E. ;

Brewer, Molly A. ;

Follen, Michele ;

Shin, Dong M. ;

Parnes, Howard L. ;

Siegfried, Jill M. ;

Evans, Alison A. ;

Blot, William J. ;

Chow, Wong-Ho ;

Blount, Patricia L. ;

Maley, Carlo C. ;

Wang, Kenneth K. ;

Lam, Stephen ;

Lee, J. Jack ;

Dubinett, Steven M. ;

Engstrom, Paul F. ;

Meyskens, Frank L., Jr. ;

O'Shaughnessy, Joyce ;

Hawk, Ernest T. ;

Levin, Bernard ;

Nelson, William G. ;

Hong, Waun Ki .

CLINICAL CANCER RESEARCH, 2006, 12 (12) :3661-3697

[8]

Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway [J].

Kensler, Thomas W. ;

Wakabayash, Nobunao ;

Biswal, Shyam .

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 2007, 47 :89-116

[9]

KHOR T, 2008, CANC PREV R IN PRESS

[10]

The role of redox-sensitive transcription factors NF-κB and AP-1 in the modulation of the Cyp1a1 gene by mercury, lead, and copper [J].

Korashy, Hesham M. ;

Ei-Kadi, Ayman O. S. .

FREE RADICAL BIOLOGY AND MEDICINE, 2008, 44 (05) :795-806