The use of GEM models for experimental cancer therapeutics

被引：34

作者：

Gopinathan, Aarthi ^{[1
]}

Tuveson, David A. ^{[1
]}

机构：

[1] Cambridge Res Inst CRUK, Cambridge CB2 0RE, England

来源：

DISEASE MODELS & MECHANISMS | 2008年 / 1卷 / 2-3期

关键词：

D O I：

10.1242/dmm.000570

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

引用

页码：83 / 86

页数：4

共 20 条

[1] Antiangiogenic versus cytotoxic therapeutic approaches to human pancreas cancer: an experimental study with a vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor and gemcitabine [J].

Bocci, G ;

Danesi, R ;

Marangoni, G ;

Fioravanti, A ;

Boggi, U ;

Esposito, I ;

Fasciani, A ;

Boschi, E ;

Campani, D ;

Bevilacqua, G ;

Mosca, F ;

Del Tacca, M .

EUROPEAN JOURNAL OF PHARMACOLOGY, 2004, 498 (1-3) :9-18

[2] Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance [J].

Boehm, T ;

Folkman, J ;

Browder, T ;

OReilly, MS .

NATURE, 1997, 390 (6658) :404-407

[3] Paradoxical roles of the immune system during cancer development [J].

de Visser, KE ;

Eichten, A ;

Coussens, LM .

NATURE REVIEWS CANCER, 2006, 6 (01) :24-37

[4] The three Es of cancer immunoediting [J].

Dunn, GP ;

Old, LJ ;

Schreiber, RD .

ANNUAL REVIEW OF IMMUNOLOGY, 2004, 22 :329-360

[5] A mouse to human search for plasma Proteome changes associated with pancreatic tumor development [J].

Faca, Vitor M. ;

Song, Kenneth S. ;

Wang, Hong ;

Zhang, Qing ;

Krasnoselsky, Alexei L. ;

Newcomb, Lisa F. ;

Plentz, Ruben R. ;

Gurumurthy, Sushma ;

Redston, Mark S. ;

Pitteri, Sharon J. ;

Pereira-Faca, Sandra R. ;

Ireton, Renee C. ;

Katayama, Hiroyuki ;

Glukhova, Veronika ;

Phanstiel, Douglas ;

Brenner, Dean E. ;

Anderson, Michelle A. ;

Misek, David ;

Scholler, Nathalie ;

Urban, Nicole D. ;

Barnett, Matt J. ;

Edelstein, Cim ;

Goodman, Gary E. ;

Thornquist, Mark D. ;

McIntosh, Martin W. ;

DePinho, Ronald A. ;

Bardeesy, Nabeel ;

Hanash, Samir M. .

PLOS MEDICINE, 2008, 5 (06) :953-967

[6] Maximizing mouse cancer models [J].

Frese, Kristopher K. ;

Tuveson, David A. .

NATURE REVIEWS CANCER, 2007, 7 (09) :645-658

[7] Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse [J].

Hingorani, SR ;

Petricoin, EF ;

Maitra, A ;

Rajapakse, V ;

King, C ;

Jacobetz, MA ;

Ross, S ;

Conrads, TP ;

Veenstra, TD ;

Hitt, BA ;

Kawaguchi, Y ;

Johann, D ;

Liotta, LA ;

Crawford, HC ;

Putt, ME ;

Jacks, T ;

Wright, CVE ;

Hruban, RH ;

Lowy, AM ;

Tuveson, DA .

CANCER CELL, 2003, 4 (06) :437-450

[8] Trp53R172H and KraSG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice [J].

Hingorani, SR ;

Wang, LF ;

Multani, AS ;

Combs, C ;

Deramaudt, TB ;

Hruban, RH ;

Rustgi, AK ;

Chang, S ;

Tuveson, DA .

CANCER CELL, 2005, 7 (05) :469-483

[9] The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies [J].

Ji, Hongbin ;

Li, Danan ;

Chen, Liang ;

Shimamura, Takeshi ;

Kobayashi, Susumu ;

McNamara, Kate ;

Mahmood, Umar ;

Mitchell, Albert ;

Sun, Yangping ;

Al-Hashem, Ruclayyah ;

Chirieac, Lucian R. ;

Padera, Robert ;

Bronson, Roderick T. ;

Kim, William ;

Janne, Pasi A. ;

Shapiro, Geoffrey I. ;

Tenen, Daniel ;

Johnson, Bruce E. ;

Weissleder, Ralph ;

Sharpless, Norman E. ;

Wong, Kwok-Kin .

CANCER CELL, 2006, 9 (06) :485-495

[10]

Jia L, 2005, WORLD J GASTROENTERO, V11, P447

← 1 2 →