RNA-protein interactions

被引：73

作者：

Hall, KB ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Dept Biochem & Mol Biophys, St Louis, MO 63110 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 2002年 / 12卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0959-440X(02)00323-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent discoveries have revealed that there is a myriad of RNAs and associated RNA-binding proteins that spatially and temporally appear in the cells of all organisms. The structures of these RNA-protein complexes are providing valuable insights into the binding modes and functional implications of these interactions. Even the common RNA-binding domains (RBDs) and the double stranded RNA binding motifs (dsRBMs) have been shown to exhibit a plethora of binding modes.

引用

页码：283 / 288

页数：6

共 36 条

[1] Solution structure of the two N-terminal RNA-binding domains of nucleolin and NMR study of the interaction with its RNA target [J].

Allain, FHT ;

Gilbert, DE ;

Bouvet, P ;

Feigon, J .

JOURNAL OF MOLECULAR BIOLOGY, 2000, 303 (02) :227-241

[2] Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin [J].

Allain, FHT ;

Bouvet, P ;

Dieckmann, T ;

Feigon, J .

EMBO JOURNAL, 2000, 19 (24) :6870-6881

[3] Novel small RNA-encoding genes in the intergenic regions of Escherichia coli [J].

Argaman, L ;

Hershberg, R ;

Vogel, J ;

Bejerano, G ;

Wagner, EGH ;

Margalit, H ;

Altuvia, S .

CURRENT BIOLOGY, 2001, 11 (12) :941-950

[4] Double-stranded RNA as a template for gene silencing [J].

Bass, BL .

CELL, 2000, 101 (03) :235-238

[5] RNA EDITING IN TRYPANOSOMES [J].

BENNE, R .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1994, 221 (01) :9-23

[6] ANALYSIS OF THE RNA-RECOGNITION MOTIF AND RS AND RGG DOMAINS - CONSERVATION IN METAZOAN PRE-MESSENGER-RNA SPLICING FACTORS [J].

BIRNEY, E ;

KUMAR, S ;

KRAINER, AR .

NUCLEIC ACIDS RESEARCH, 1993, 21 (25) :5803-5816

[7] Cloning and characterization of two guide RNA-binding proteins from mitochondria of Crithidia fasciculata:: gBP27, a novel protein, and gBP29, the orthologue of Trypanosoma brucei gBP21 [J].

Blom, D ;

van den Burg, J ;

Breek, CKD ;

Speijer, D ;

Muijsers, AO ;

Benne, R .

NUCLEIC ACIDS RESEARCH, 2001, 29 (14) :2950-2962

[8] Recognition of pre-formed and flexible elements of an RNA stem-loop by nucleolin [J].

Bouvet, P ;

Allain, FHT ;

Finger, LD ;

Dieckmann, T ;

Feigon, J .

JOURNAL OF MOLECULAR BIOLOGY, 2001, 309 (03) :763-775

[9] RNA-BINDING SPECIFICITY OF HNRNP A1 - SIGNIFICANCE OF HNRNP A1 HIGH-AFFINITY BINDING-SITES IN PRE-MESSENGER-RNA SPLICING [J].

BURD, CG ;

DREYFUSS, G .

EMBO JOURNAL, 1994, 13 (05) :1197-1204

[10] Purification and properties of HuD, a neuronal RNA-binding protein [J].

Chung, SM ;

Jiang, L ;

Cheng, S ;

Furneaux, H .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (19) :11518-11524

← 1 2 3 4 →