Measles elimination in Canada

被引：47

作者：

King, A

Varughese, P

De Serres, G

Tipples, GA

Waters, J

机构：

[1] Hlth Canada, Immunizat & Resp Dis Div, Ctr Infect Dis Prevent & Control, Populat & Publ Hlth Branch, Ottawa, ON K1A 0K9, Canada

[2] Univ Laval, Publ Hlth Res Unit, Quebec City, PQ G1K 7P4, Canada

[3] Inst Natl Sante Publ Quebec, Quebec City, PQ, Canada

[4] Hlth Canada, Populat & Publ Hlth Branch, Natl Microbiol Lab, Winnipeg, MB, Canada

[5] Alberta Hlth & Wellness, Hlth Strategies Div, Edmonton, AB, Canada

来源：

JOURNAL OF INFECTIOUS DISEASES | 2004年 / 189卷

关键词：

D O I：

10.1086/378499

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To describe the progress and challenges in achieving measles elimination in Canada, we analyzed national data on measles cases for 1998-2001. To assess the status of measles elimination in Canada, we estimated the effective reproductive number, R. Measles elimination was defined as the interruption of endemic transmission and failure to reestablish endemic transmission after importation. Twelve isolated cases, 29 cases (72.4% were linked to 2 outbreaks), 199 cases (96.9% were linked to 4 outbreaks of 2, 6, 30, and 155 cases), and 34 cases (73.5% were linked to 8 outbreaks of 2, 2, 2, 2, 3, 3, 3, and 8 cases) were reported in 1998, 1999, 2000, and 2001, respectively. R ranged from 0.58 to 0.95. Multiple chains of transmission occurred in religious communities that actively oppose or resist immunization efforts. Epidemiological and virological evidence suggests that endemic transmission of measles has been mostly interrupted since 1998.

引用

页码：S236 / S242

页数：7

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