RETRACTED: Postarthroscopic meniscus repair analgesia with intraarticular ketorolac or morphine (Retracted Article)

被引:51
作者
Reuben, SS
Connelly, NR
机构
[1] Department of Anesthesiology, School of Medicine, Tufts University, Springfield, MA
[2] Department of Anesthesiology, Baystate Medical Center, Springfield, MA 01199
关键词
D O I
10.1097/00000539-199605000-00027
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Both ketorolac, a nonsteroidal antiinflammatory drug, and morphine, an opioid agonist, provide enhanced patient analgesia after arthroscopic knee surgery when administered via the intraarticular route. This study was designed to determine whether ketorolac or morphine results in better patient analgesia and whether their combination would provide superior analgesia to either drug alone. Patients undergoing arthroscopic knee meniscus repair under local anesthesia with sedation were evaluated. Each of the study groups evaluated received ketorolac (either via the parenteral or intraarticular route) and morphine (via either the parenteral or intraarticular route). This study revealed a significant benefit from the individual intraarticular administration of both morphine and ketorolac. The combination of these drugs did not result in decreased postoperative pain or need for postoperative analgesics, and it did not result in an increased analgesic duration. We conclude that the use of either intraarticular ketorolac or intraarticular morphine improves comfort in patients undergoing arthroscopic meniscus repair and that their combination offers no advantage over either drug alone.
引用
收藏
页码:1036 / 1039
页数:4
相关论文
共 14 条
[1]   POSTARTHROSCOPY ANALGESIA WITH INTRAARTICULAR BUPIVACAINE MORPHINE - A RANDOMIZED CLINICAL-TRIAL [J].
ALLEN, GC ;
STAMAND, MA ;
LUI, ACP ;
JOHNSON, DH ;
LINDSAY, MP .
ANESTHESIOLOGY, 1993, 79 (03) :475-480
[2]  
BJORNSSON A, 1994, REGION ANESTH, V19, P104
[3]   LOW-DOSE INTRAARTICULAR MORPHINE ANALGESIA IN DAY-CASE KNEE ARTHROSCOPY - A RANDOMIZED DOUBLE-BLINDED PROSPECTIVE-STUDY [J].
DALSGAARD, J ;
FELSBY, S ;
JUELSGAARD, P ;
FROEKJAER, J .
PAIN, 1994, 56 (02) :151-154
[4]  
FEREIRRA SH, 1979, PROSTAGLANDINS, V18, P191
[5]  
HEARD SO, 1992, ANESTH ANALG, V74, P822
[6]  
JORIS JL, 1987, ANESTH ANALG, V66, P1277
[7]   INTRAARTICULAR MORPHINE, BUPIVACAINE, AND MORPHINE BUPIVACAINE FOR PAIN CONTROL AFTER KNEE VIDEOARTHROSCOPY [J].
KHOURY, GF ;
CHEN, ACN ;
GARLAND, DE ;
STEIN, C .
ANESTHESIOLOGY, 1992, 77 (02) :263-266
[8]   COMPARISON OF POSTOPERATIVE ANALGESIC EFFECTS OF INTRAARTICULAR BUPIVACAINE AND MORPHINE FOLLOWING ARTHROSCOPIC KNEE SURGERY [J].
RAJA, SN ;
DICKSTEIN, RE ;
JOHNSON, CA .
ANESTHESIOLOGY, 1992, 77 (06) :1143-1147
[9]   POSTOPERATIVE ANALGESIA FOR OUTPATIENT ARTHROSCOPIC KNEE SURGERY WITH INTRAARTICULAR BUPIVACAINE AND KETOROLAC [J].
REUBEN, SS ;
CONNELLY, NR .
ANESTHESIA AND ANALGESIA, 1995, 80 (06) :1154-1157
[10]   OPIOIDS FROM IMMUNOCYTES INTERACT WITH RECEPTORS ON SENSORY NERVES TO INHIBIT NOCICEPTION IN INFLAMMATION [J].
STEIN, C ;
HASSAN, AHS ;
PRZEWLOCKI, R ;
GRAMSCH, C ;
PETER, K ;
HERZ, A .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (15) :5935-5939