Channel noise in neurons

被引：522

作者：

White, JA ^{[1
]}

Rubinstein, JT

Kay, AR

机构：

[1] Boston Univ, Dept Biomed Engn, Boston, MA 02215 USA

[2] Boston Univ, Ctr Biodynam, Boston, MA 02215 USA

[3] Univ Iowa, Coll Med, Dept Otolaryngol Head & Neck Surg, Iowa City, IA 52242 USA

[4] Univ Iowa, Coll Med, Dept Physiol & Biophys, Iowa City, IA 52242 USA

[5] Univ Iowa, Dept Biol Sci, Iowa City, IA 52242 USA

来源：

TRENDS IN NEUROSCIENCES | 2000年 / 23卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0166-2236(99)01521-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The probabilistic gating of voltage-dependent ion channels is a source of electrical 'channel noise' in neurons. This noise has long been implicated in limiting the reliability (repeatability) of neuronal responses to repeated presentations of identical stimuli. More recently, it has been shown to increase the range of spiking behaviors exhibited in some neural populations. Channel numbers are tied to metabolic efficiency and the stability of resting potential, and channel noise might be exploited by future cochlear implants in order to improve the temporal representation of sound.

引用

页码：131 / 137

页数：7

共 70 条

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