Improvement in the management of chronic heart failure since the publication of the updated guidelines of the European Society of Cardiology The Impact-Reco Programme

被引:45
作者
de Groote, Pascal [2 ]
Isnard, Richard [1 ]
Clerson, Pierre [4 ]
Jondeau, Guillaume [3 ]
Galinier, Michel [5 ]
Assyag, Patrick [6 ]
Demill, Nacima [7 ]
Ducardonnet, Alain [8 ]
Thebaut, Jean-Francois [9 ]
Komajda, Michel [1 ]
机构
[1] Univ Paris 06, Dept Cardiol, Pitie Salpetriere Hosp, AP HP, F-75651 Paris 13, France
[2] Univ Lille 2, CHRU, F-59800 Lille, France
[3] Univ Paris 07, Hop Bichat, AP HP, Serv Cardiol, Paris, France
[4] Orgametrie, Roubaix, France
[5] CHU Rangueil, Fed Serv Cardiol, F-31054 Toulouse, France
[6] Hop St Antoine, Serv Cardiol, F-75571 Paris, France
[7] Astra Zeneca, Rueil Malmaison, France
[8] Inst Caeur Effort Sante, Paris, France
[9] Ctr Alfred Kastler, Sarcelles, France
关键词
Chronic heart failure; Drug prescription; Angiotensin-converting enzyme-inhibitors; Beta-blockers; Angiotensin 2 receptor blockers; Guidelines; VENTRICULAR SYSTOLIC DYSFUNCTION; CONVERTING-ENZYME-INHIBITORS; TRIAL; CANDESARTAN; MORBIDITY; HOSPITALS; MORTALITY; ADHERENCE; DIAGNOSIS; DISCHARGE;
D O I
10.1093/eurjhf/hfn005
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aims Recent studies have shown that prescription rates and doses of recommended drugs for chronic heart failure (CHF) are not optimal in daily practice. The aim of the Impact-Reco programme was to analyse prescription rates of CHF drugs in stable outpatients with CHF related to left ventricular (LV) systolic dysfunction in two similar surveys in France. Methods and results The two surveys, which included 1917 and 1974 patients, were performed between September 2004 to March 2005 and September 2005 to May 2006, respectively. Prescription rates of angiotensin-converting enzyme-inhibitors (ACE-1) remained stable (71 vs. 68%, respectively), whereas the proportion of patients receiving angiotensin receptor blockers (21 vs. 30%, P < 0.0001) and beta-blockers (65 vs. 70% P < 0.0001) increased significantly. Doses of ACE-1 and beta-blockers increased significantly between the two surveys. However, the improvement was of lesser magnitude in some subgroups of patients, such as elderly patients or patients with renal failure. Conclusion The Impact-Reco programme found an improvement in prescription rates and in the dosage of neurohumoral antagonists in French outpatients with stable CHF. However, there is still room for improvement, especially regarding the doses of medications and the treatment of some subgroups of patients such as the elderly and patients with renal failure.
引用
收藏
页码:85 / 91
页数:7
相关论文
共 30 条
[1]   Management of heart failure in primary care (the IMPROVEMENT of Heart Failure Programme): an international survey [J].
Cleland, JGF ;
Cohen-Solal, A ;
Aguilar, JC ;
Dietz, R ;
Eastaugh, J ;
Follath, F ;
Freemantle, N ;
Gavazzi, A ;
van Gilst, WH ;
Hobbs, FDR ;
Korewicki, J ;
Madeira, HC ;
Preda, I ;
Swedberg, K ;
Widimsky, J .
LANCET, 2002, 360 (9346) :1631-1639
[2]   Is the prognosis of heart failure improving? [J].
Cleland, JGF ;
Gemmell, I ;
Khand, A ;
Boddy, A .
EUROPEAN JOURNAL OF HEART FAILURE, 1999, 1 (03) :229-241
[3]   A national survey of heart failure in French hospitals [J].
Cohen-Solal, A ;
Desnos, M ;
Delahaye, F ;
Emeriau, JP ;
Hanania, G .
EUROPEAN HEART JOURNAL, 2000, 21 (09) :763-769
[4]  
Cowie MR, 1997, EUR HEART J, V18, P208
[5]   Is the gap between guidelines and clinical practice in heart failure treatment being filled?: Insights from the IMPACT RECO survey [J].
de Groote, P. ;
Isnard, R. ;
Assyag, P. ;
Clerson, P. ;
Ducardonnet, A. ;
Galinier, M. ;
Jondeau, G. ;
Leurs, I. ;
Thebaut, J. -F. ;
Komajda, M. .
EUROPEAN JOURNAL OF HEART FAILURE, 2007, 9 (12) :1205-1211
[6]   Determinants of angiotensin-converting enzyme inhibitor prescription in severe heart failure with left ventricular systolic dysfunction:: The EPICAL study [J].
Echemann, M ;
Zannad, F ;
Briançon, S ;
Juillière, Y ;
Mertès, PM ;
Virion, JM ;
Villemot, JP .
AMERICAN HEART JOURNAL, 2000, 139 (04) :624-631
[7]   Improving the use of evidence-based heart failure therapies in the outpatient setting: The IMPROVE HF performance improvement registry [J].
Fonarow, Gregg C. ;
Yancy, Clyde W. ;
Albert, Nancy M. ;
Curtis, Anne B. ;
Stough, Wendy Gattis ;
Gheorghlade, Mihai ;
Heywood, J. Thomas ;
Mehra, Mandeep ;
O'Connor, Christopher M. ;
Reynolds, Dwight ;
Walsh, Mary Norine .
AMERICAN HEART JOURNAL, 2007, 154 (01) :12-38
[8]   Adherence to candesartan and placebo and outcomes in chronic heart failure in the CHARM programme: double-blind, randomised, controlled clinical trial [J].
Granger, BB ;
Swedberg, K ;
Ekman, I ;
Granger, CB ;
Olofsson, B ;
McMurray, JJV ;
Yusuf, S ;
Michelson, EL ;
Pfeffer, MA .
LANCET, 2005, 366 (9502) :2005-2011
[9]   Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors:: the CHARM-Alternative trial [J].
Granger, CB ;
McMurray, JJV ;
Yusuf, S ;
Held, P ;
Michelson, EL ;
Olofsson, B ;
Östergren, J ;
Pfeffer, MA ;
Swedberg, K .
LANCET, 2003, 362 (9386) :772-776
[10]   Heart failure due to left ventricular systolic dysfunction:: Treatment at discharge from hospital and at one year [J].
Houpe, D ;
Peltier, M ;
Cohen-Solal, A ;
Béguin, M ;
Lévy, F ;
Slama, M ;
Chapelain, K ;
Tribouilloy, C .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2005, 103 (03) :286-292