In vitro Fosfomycin Activity in Vancomycin-Resistant Enterococcus faecalis

被引：6

作者：

Superti, Silvana ^{[1
]}

Gomes Dias, Cicero Armidio ^{[2
]}

d'Azevedo, Pedro Alves ^{[1
,2
]}

机构：

[1] Fed Univ Porto Alegre, Postgraduat Program Pathol Hlth Sci, Porto Alegre, RS, Brazil

[2] Fed Univ Porto Alegre, Dept Microbiol & Parastiol Hlth Sci, Porto Alegre, RS, Brazil

来源：

BRAZILIAN JOURNAL OF INFECTIOUS DISEASES | 2009年 / 13卷 / 02期

关键词：

Enterococcus faecalis; vancomycin-resistance; VRE; fosfomycin; INFECTIONS;

D O I：

10.1590/S1413-86702009000200010

中图分类号：

R51 [传染病];

学科分类号：

100201 [内科学];

摘要：

Enterococci are part of the endogenous flora of human beings, are naturally resistant to several classes of antimicrobials, and are able to acquire resistance with relative case. Currently the vancomycin-resistant enterococci are spread all over the world and treatment options for infections caused by it are often extremely limited. We assessed 193 vancomycin-resistant Enterococcus faecalis isolates collected from four different hospitals in Porto Alegre for their susceptibility to fosfomycin using the E-test and agar diffusion. Fosfomycin proved to be active in vitro against the great majority of isolates, indicating that it is a valid option in the treatment of these infections.

引用

页码：123 / 124

页数：2

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