学术探索
学术期刊
新闻热点
数据分析
智能评审

Overcoming adeno-associated virus vector size limitation through viral DNA heterodimerization

被引：178
作者：
Sun, LW
Li, J
Xiao, X
机构：
[1] Univ Pittsburgh, Dept Mol Genet & Biochem, Pittsburgh, PA 15261 USA
[2] Univ Pittsburgh, Gene Therapy Ctr, Pittsburgh, PA 15261 USA
[3] Univ Pittsburgh, Duchenne Muscular Dystrophy Res Ctr, Pittsburgh, PA 15261 USA
[4] Univ Pittsburgh, Dept Orthoped Surg, Pittsburgh, PA 15261 USA
来源：
NATURE MEDICINE | 2000年 / 6卷 / 05期
关键词：
D O I：
10.1038/75087
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：599 / 602
页数：4
相关论文
共 25 条
  • [1] INTEGRATION OF THE ADENO-ASSOCIATED VIRUS GENOME INTO CELLULAR DNA IN LATENTLY INFECTED HUMAN DETROIT-6 CELLS
    CHEUNG, AKM
    HOGGAN, MD
    HAUSWIRTH, WW
    BERNS, KI
    [J]. JOURNAL OF VIROLOGY, 1980, 33 (02) : 739 - 748
  • [2] Quantitative analysis of the packaging capacity of recombinant adeno-associated virus
    Dong, JY
    Fan, PD
    Frizzell, RA
    [J]. HUMAN GENE THERAPY, 1996, 7 (17) : 2101 - 2112
  • [3] Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue
    Duan, DS
    Sharma, P
    Yang, JS
    Yue, YP
    Dudus, L
    Zhang, YL
    Fisher, KJ
    Engelhardt, JF
    [J]. JOURNAL OF VIROLOGY, 1998, 72 (11) : 8568 - 8577
  • [4] Structural analysis of adeno-associated virus transduction circular intermediates
    Duan, DS
    Yan, ZY
    Yue, YP
    Engelhardt, JF
    [J]. VIROLOGY, 1999, 261 (01) : 8 - 14
  • [5] Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue (vol 72, pg 8568, 1998)
    Duan, DS
    Sharma, P
    Yang, JS
    Yue, YP
    Dudus, L
    Zhang, YL
    Fisher, KJ
    Engelhardt, JF
    [J]. JOURNAL OF VIROLOGY, 1999, 73 (01) : 861 - 861
  • [6] In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector
    During, MJ
    Samulski, RJ
    Elsworth, JD
    Kaplitt, MG
    Leone, P
    Xiao, X
    Li, J
    Freese, A
    Taylor, JR
    Roth, RH
    Sladek, JR
    O'Malley, KL
    Redmond, DE
    [J]. GENE THERAPY, 1998, 5 (06) : 820 - 827
  • [7] STABLE IN-VIVO EXPRESSION OF THE CYSTIC-FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR WITH AN ADENOASSOCIATED VIRUS VECTOR
    FLOTTE, TR
    AFIONE, SA
    CONRAD, C
    MCGRATH, SA
    SOLOW, R
    OKA, H
    ZEITLIN, PL
    GUGGINO, WB
    CARTER, BJ
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (22) : 10613 - 10617
  • [8] FLOTTE TR, 1993, J BIOL CHEM, V268, P3781
  • [9] SELECTIVE EXTRACTION OF POLYOMA DNA FROM INFECTED MOUSE CELL CULTURES
    HIRT, B
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 1967, 26 (02) : 365 - &
  • [10] DYSTROPHIN - THE PROTEIN PRODUCT OF THE DUCHENNE MUSCULAR-DYSTROPHY LOCUS
    HOFFMAN, EP
    BROWN, RH
    KUNKEL, LM
    [J]. CELL, 1987, 51 (06) : 919 - 928
123