Acyclic structural variants of growth hormone secretagogue L-692,429

被引:8
作者
Lin, P
Pisano, JM
Schoen, WR
Cheng, K
Chan, WWS
Butler, BS
Smith, RG
Fisher, MH
Wyvratt, MJ
机构
[1] Merck Res Labs, Dept Med Chem, Rahway, NJ 07065 USA
[2] Merck Res Labs, Dept Biochem & Physiol, Rahway, NJ 07065 USA
关键词
D O I
10.1016/S0960-894X(99)00568-5
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Systematic investigation of acyclic analogs of L-692,429, the prototype benzolactam growth hormone secretagogue, has helped to further define the structural requirements for the release of growth hormone from rat pituitary cells for this class of secretagogues. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:3237 / 3242
页数:6
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