Diagnosis and Treatment of Acquired Aplastic Anemia

被引：41

作者：

Bacigalupo, Andrea ^{[1
]}

Passweg, Jakob ^{[2
]}

机构：

[1] Osped San Martino Largo, Div Ematol & Trapianto Midollo Osseo, I-16132 Genoa, Italy

[2] Hop Cantonal Univ Geneva, Serv Hematol, Geneva, Switzerland

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2009年 / 23卷 / 02期

关键词：

Antithymocyte globulin; Hemopoietic stem cell transplantation; Bone marrow failure; Cyclosporine; Growth factors; BONE-MARROW-TRANSPLANTATION; STEM-CELL TRANSPLANTATION; COLONY-STIMULATING FACTOR; IMMUNOSUPPRESSIVE THERAPY; ANTILYMPHOCYTE GLOBULIN; UNRELATED DONORS; CYCLOSPORINE-A; FOLLOW-UP; ANTITHYMOCYTE GLOBULIN; RANDOMIZED-TRIAL;

D O I：

10.1016/j.hoc.2009.01.005

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Acquired severe aplastic; anemia can be treated successfully with either immunosuppressive therapy or bone marrow transplantation. Although immunosuppressive therapy can be readily administered to all patients, it is not a curative approach and is associated with a higher risk of clonal evolution than is transplantation, which yields rapid and long-lasting hematologic remission. This article reviews the key diagnostic and prognostic factors that influence the choice of therapy in patients with acquired aplastic: anemia.

引用

页码：159 / +

页数：13

共 43 条

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