Synthesis of novel spirolactams by reaction of fluorescein methyl ester with amines

被引:25
作者
Adamczyk, M [1 ]
Grote, J [1 ]
机构
[1] Abbott Labs, Div Organ Chem Res, Dept 9NM, Abbott Pk, IL 60064 USA
关键词
D O I
10.1016/S0040-4039(99)02197-8
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A family of previously undescribed fluorescein spirolactams was synthesized by reaction of fluorescein methyl ester with a variety of primary amines. The structure of the non-fluorescent spirolactams was elucidated by NMR spectroscopy and X-ray crystallography. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:807 / 809
页数:3
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