Transplantation of hematopoietic stem cells from alternate donors in acute myelogenous leukemia

被引：13

作者：

Anasetti, C

机构：

[1] Fred Hutchinson Canc Res Ctr, Div Clin Res, Seattle, WA 98104 USA

[2] Univ Washington, Seattle, WA 98109 USA

来源：

LEUKEMIA | 2000年 / 14卷 / 03期

关键词：

AML; allotransplantation;

D O I：

10.1038/sj.leu.2401648

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The number of allogeneic transplants from unrelated donors has grown in the past decade in part because of the expansion of the donor registry size. Patient survival has improved due to the selection of more closely matched donors and the development of effective infection prophylaxis. Relapse-free survival remains limited in patients with a large tumor burden at the time of transplantation. A higher marrow cell dose is the major factor to minimize transplant-related death. Future studies of peripheral blood stem cell transplants should be considered for patients with acute leukemia with the goal of enhancing the stem cell dose and improving survival.

引用

页码：502 / 504

页数：3

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