One- and Two-Photon Excitation of β-Carbolines in Aqueous Solution: pH-Dependent Spectroscopy, Photochemistry, and Photophysics

被引：60

作者：

Micaela Gonzalez, M. ^{[2
]}

Arnbjerg, Jacob ^{[1
]}

Paula Denofrio, M. ^{[3
]}

Erra-Balsells, Rosa ^{[2
]}

Ogilby, Peter R. ^{[1
]}

Cabrerizo, Franco M. ^{[2
]}

机构：

[1] Aarhus Univ, Dept Chem, Ctr Oxygen Microscopy & Imaging, DK-8000 Aarhus, Denmark

[2] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Quim Organ, CIHIDECAR CONICET, RA-1428 Buenos Aires, DF, Argentina

[3] Univ Nacl La Plata, Fac Ciencias Exactas, Dept Quim, INIFTA CONICET CIC, RA-1900 La Plata, Argentina

来源：

JOURNAL OF PHYSICAL CHEMISTRY A | 2009年 / 113卷 / 24期

基金：

新加坡国家研究基金会;

关键词：

SINGLET OXYGEN; MOLECULAR-OXYGEN; ACID-BASE; RESONANCE ENHANCEMENT; FLUORESCENCE-SPECTRA; INDUCED MUTAGENESIS; ELECTRONIC-SPECTRA; AROMATIC KETONES; PROTON-TRANSFER; CROSS-SECTIONS;

D O I：

10.1021/jp902105x

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

beta-Carboline (beta C) alkaloids are present in a wide range of biological systems and play a variety of significant photodependent roles. In this work, a study of the aqueous solution-phase photochemistry, photophysics, and spectroscopy of three important beta Cs [norharmane (nHo), harmane (Ho), and harmine (Ha)] and two beta C derivatives [N-methylnorharmane (N-Me-nHo) and N-methylharmane (N-Me-Ho)] upon one- and two-photon excitation is presented. The results obtained depend significantly on pH, the ambient oxygen concentration, and the beta C substituent and provide unique insight into a variety of fundamental photophysical phenomena. The data reported herein should not only help to understand the roles played by beta C alkaloids in biological systems but should also help in the development of methods by which the photoinduced behavior of these important compounds can be controlled.

引用

页码：6648 / 6656

页数：9

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