Synthesis of dimeric lactose and dimeric (sialyl) LewisX glycolipids

被引：2

作者：

Gege, C ^{[1
]}

Schmidt, RR ^{[1
]}

机构：

[1] Univ Konstanz, Fachbereich Chem, D-78457 Constance, Germany

来源：

CARBOHYDRATE RESEARCH | 2002年 / 337卷 / 12期

关键词：

carbohydrate-carbohydrate interaction; Lewis antigen; neoglycolipids; molecular recognition;

D O I：

10.1016/S0008-6215(02)00086-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

To investigate structural requirements for the homophilic interaction between carbohydrates on planar model membranes, divalent derivatives with enforced proximity between the two carbohydrate epitopes (lactose, Lewis(X), and sialyl Lewis(X)) were synthesized by use of a dimeric membrane anchor as scaffold. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1089 / 1094

页数：6

共 28 条

[1] COSY cross-peaks from 1H-1H dipolar couplings in NMR spectra of field oriented oligosaccharides [J].

Bolon, PJ ;

Prestegard, JH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (36) :9366-9367

[2] SYNTHESIS OF LD-HEPP AND KDO CONTAINING DISACCHARIDE AND TETRASACCHARIDE DERIVATIVES OF NEISSERIA-MENINGITIDIS INNER-CORE REGION VIA IODONIUM ION PROMOTED GLYCOSIDATIONS [J].

BOONS, GJPH ;

VANDELFT, FL ;

VANDERKLEIN, PAM ;

VANDERMAREL, GA ;

VANBOOM, JH .

TETRAHEDRON, 1992, 48 (05) :885-904

[3]

Cong Y, UNPUB

[4]

de la Fuente J.M., 2001, ANGEW CHEM, V773, P2317, DOI DOI 10.1021/ac062341m

[5]

de la Fuente JM, 2001, ANGEW CHEM INT EDIT, V40, P2258, DOI 10.1002/1521-3773(20010618)40:12<2257::AID-ANIE2257>3.0.CO

[6]

2-S

[7]

DEHMLOW EV, 1989, LIEBIGS ANN CHEM, P181

[8]

ERNST B, 2001, CARBOHYDRATES CHEM B

[9] Synthesis of new lipophilic ortho-dicarboranes [J].

Garrigues, E ;

Souchard, JP ;

Nepveu, F .

TETRAHEDRON LETTERS, 1998, 39 (25) :4489-4492

[10] Synthesis of fluorescence labeled sialyl Lewisx glycosphingolipids [J].

Gege, C ;

Oscarson, S ;

Schmidt, RR .

TETRAHEDRON LETTERS, 2001, 42 (03) :377-380

← 1 2 3 →