Scorzonerosides A, B, and C, novel triterpene, oligoglycosides with hepatoprotective effect from Chinese Bupleuri Radix, the roots of Bupleurum scorzonerifolium Willd

被引：37

作者：

Yoshikawa, M

Murakami, T

Hirano, K

Inadzuki, M

Ninomiya, K

Matsuda, H

机构：

[1] Kyoto Pharmaceutical University, Kyoto 607, 5, Nakauchi-cho, Misasagi

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 42期

关键词：

D O I：

10.1016/S0040-4039(97)01733-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Triterpene glycoside adonitol esters, scorzonerosides A, B, and C, were isolated from Chinese Bupleuri Radix, the roots of Bupleurum scorzonerifolium. Their absolute stereostructures were elucidated on the physicochemical and chemical evidence, which included the synthesis of the adonitol moiety from D-ribose. Scorzonerosides A, B, and C were found to show hepatoprotective effect on liver injury induced by D-galactosamine and lipopolysaccharide in mice. (C) 1997 Elsevier Science Ltd.

引用

页码：7395 / 7398

页数：4

共 9 条

[1]

HARA S, 1986, CHEM PHARM BULL, V34, P1843

[2]

KUBOTA TOKUO, 1966, TETRAHEDRON LETT, V39, P4725

[3] POLYACETYLENES FROM ROOTS OF BUPLEURUM-FALCATUM [J].