HIV and Tfh Cells: Circulating New Ideas to Identify and Protect

被引：12

作者：

Chahroudi, Ann ^{[1
,3
]}

Silvestri, Guido ^{[2
,3
,4
]}

机构：

[1] Emory Univ, Sch Med, Dept Pediat, Atlanta, GA 30322 USA

[2] Emory Univ, Sch Med, Dept Pathol, Atlanta, GA 30322 USA

[3] Emory Univ, Yerkes Natl Primate Res Ctr, Atlanta, GA 30329 USA

[4] Emory Univ, Emory Vaccine Ctr, Atlanta, GA 30329 USA

来源：

IMMUNITY | 2016年 / 44卷 / 01期

关键词：

ANTIBODY-RESPONSES; INFECTION;

D O I：

10.1016/j.immuni.2015.12.016

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

T follicular helper (Tfh) cells provide crucial support to antigen-specific B cells. In this issue of Immunity, Schultz et al. (2016) report that circulating IL-21-producing CD4(+) T cells are phenotypically, transcriptionally, and functionally similar to lymphoid Tfh cells and that such HIV-specific Tfh cells were increased in RV144 trial vaccine recipients.

引用

页码：16 / 18

页数：3

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