The critical micelle concentrations of lysophosphatidic acid and sphingosylphosphorylcholine

被引:33
作者
Li, ZG [1 ]
Mintzer, E [1 ]
Bittman, R [1 ]
机构
[1] CUNY Queens Coll, Dept Chem & Biochem, Flushing, NY 11367 USA
关键词
micelles; lysophosphatidic acid sphingosylphosphoryleholine;
D O I
10.1016/j.chemphyslip.2004.03.001
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The critical micelle concentrations (CMC) of lysophosphatidic acid (LPA) and sphingosylphosphorylcholine (SPC) were measured by isothermal titration calorimetry. The CMC of LPA decreases with salt concentration and acyl chain length. In water at 25 degreesC, the CMC values of 1-acyl-2-lyso-sn-glycero-3-phosphatidic acid are 1.850, 0.540, 0.082, and 0.346 mM, respectively, when the acyl group is myristoyl, palmitoyl, stearoyl, and oleoyl. The CMC of SPC in 10 mM sodium phosphate buffer, pH 7.4, at 25 degreesC was 0.158 mM, and did not change with an increase in salt concentration. (C) 2004 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:197 / 201
页数:5
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