Different allyl 2-lithloaryl ethers undergo a tandem carbolithiation/gamma-elimination in Et2O/TMEDA affording o-cyclopropyl phenol or naphthol derivatives in a diastereoselective manner. The use of (-)-sparteine as a chiral ligand instead of TMEDA allows the synthesis of cyclopropane derivatives with up 81% ee.
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页码:2225 / 2228
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[1]
[Anonymous], STEREOSELECTIVE SYNT
[2]
Ashweek NJ, 2002, CHEM-EUR J, V8, P195, DOI 10.1002/1521-3765(20020104)8:1<195::AID-CHEM195>3.0.CO
[3]
2-H
[4]
Bailey W. F., 1994, ADV DETAILED REACTIO, V3, P251