Prins cyclizations in Au-catalyzed reactions of enynes

被引：183

作者：

Jimenez-Nunez, Eloisa ^{[1
]}

Claverie, Christelle K. ^{[1
]}

Nieto-Oberhuber, Cristina ^{[1
]}

Echavarren, Antonio M. ^{[1
]}

机构：

[1] Inst Chem Res Catalonia ICIQ, Tarragona 43007, Spain

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 33期

关键词：

cyclization; enynes; gold; Prins reaction; rearrangements;

D O I：

10.1002/anie.200601575

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Going for gold: AuI-catalyzed cyclizations of functionalized enynes lead to the ready assembly of tricyclic carbon skeletons that are present in a number of naturally occurring compounds. An alkenyl gold intermediate is formed in the cyclization of the enynes and can be trapped in 5-exo-dig or 6-endo-dig Prins reactions to form an additional C-C bond. Z = C(CO 2Me)2, NTs; R = H, Me, iPr. (Chemical Equation Presented). © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：5452 / 5455

页数：4

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